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Legend Biotech’s Earnings Call Highlights Growth and Optimism

Legend Biotech Corporation ((LEGN)) has held its Q1 earnings call. Read on for the main highlights of the call.

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Legend Biotech Corporation’s recent earnings call reflects a strong positive momentum, characterized by significant sales growth, operational efficiency, and strategic expansions in global markets. Despite challenges related to net loss and exchange rate impacts, the company maintains an optimistic outlook with a solid financial position and promising developments in the CAR-T space.

CARVYKTI Net Trade Sales Surge

Net trade sales for CARVYKTI reached approximately $369 million, marking a remarkable 135% increase year-over-year. This surge underscores the product’s strong market performance and its pivotal role in driving the company’s revenue growth.

Expansion in Global Markets

Legend Biotech has demonstrated robust performance outside the U.S., with sales reaching $51 million, more than doubling compared to the same period last year. This growth is driven by strategic expansions in Germany, Switzerland, Austria, and Brazil, highlighting the company’s successful international market penetration.

Operational Efficiency Improvements

The company reported a significant reduction in operating loss, which decreased by more than half from $118 million to $51 million year-over-year. This improvement is attributed to enhanced operational efficiency and disciplined expense management, reflecting Legend Biotech’s commitment to financial prudence.

Manufacturing Success Rate

Legend Biotech achieved a 97% manufacturing success rate and a 95% timely delivery rate, with a decreasing median turnaround time now at 30 days. These metrics demonstrate the company’s operational excellence and its ability to meet market demand efficiently.

Cash Reserves and Financial Health

The company maintains a strong cash position of approximately $1 billion, which supports its operations until profitability is anticipated in 2026. This financial health provides a solid foundation for continued investment in growth initiatives.

Regulatory Approvals and Clinical Advancements

CARVYKTI received approval in Australia for the second line plus setting, and overall survival was added to the EMA label. These regulatory milestones enhance the product’s market potential and clinical credibility.

Net Loss for the Quarter

Legend Biotech reported a net loss of $101 million for the quarter. However, after excluding non-core business items, the adjusted net loss was $27 million, indicating a more favorable financial position.

Exchange Rate Impact

The company experienced a $52 million unrealized foreign exchange loss due to treasury operations based in Ireland. This impact highlights the challenges of operating in a global financial environment.

Outpatient Setting Adoption

While over half of CARVYKTI usage is in outpatient settings, progress in this area has been slow, with growth in single-digit percentage points. This indicates potential for further market penetration and adoption.

Forward-Looking Guidance

During Legend Biotech’s Q1 2025 earnings call, the company provided optimistic guidance. It aims for CARVYKTI to achieve operational breakeven by the end of 2025 and anticipates company-wide profitability in 2026. With a strong cash position, Legend continues to invest in expanding manufacturing capacities and advancing its pipeline programs, aligning with its strategic priorities for long-term growth.

In summary, Legend Biotech’s earnings call highlights a positive trajectory with significant sales growth and strategic expansions. The company’s strong financial health and operational efficiency improvements position it well for future profitability. Despite challenges, the overall sentiment remains optimistic, with promising developments in the CAR-T space.

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