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Cellectis Unveils Promising Phase 1 Results for Lasme-cel in r/r B-ALL

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Cellectis Unveils Promising Phase 1 Results for Lasme-cel in r/r B-ALL

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Cellectis SA ( (CLLS) ) has provided an announcement.

On October 16, 2025, Cellectis S.A. hosted an Investors R&D Day, unveiling promising data from the Phase 1 BALLI-01 study of lasme-cel (UCART22) for patients with relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL). The study showed lasme-cel was generally well-tolerated and demonstrated significant efficacy, with a 68% overall response rate and 83% achieving minimal residual disease-negative status in the target Phase 2 population. The company announced the initiation of the pivotal Phase 2 trial and outlined a registration path for lasme-cel as a bridge to transplant in r/r ALL, with a Biologics License Application submission anticipated in 2028. This development positions lasme-cel as a potential game-changer in the industry, offering a new treatment option for heavily pretreated patients and potentially capturing a significant share of the market.

The most recent analyst rating on (CLLS) stock is a Buy with a $8.00 price target. To see the full list of analyst forecasts on Cellectis SA stock, see the CLLS Stock Forecast page.

Spark’s Take on CLLS Stock

According to Spark, TipRanks’ AI Analyst, CLLS is a Neutral.

Cellectis SA’s overall stock score is driven by positive technical momentum and encouraging earnings call sentiment, particularly regarding clinical trial progress and strategic partnerships. However, financial performance challenges and valuation uncertainties due to ongoing losses weigh on the score.

To see Spark’s full report on CLLS stock, click here.

More about Cellectis SA

Cellectis S.A. is a clinical-stage biotechnology company that utilizes its pioneering gene editing platform to develop life-saving cell and gene therapies. The company focuses on creating allogeneic CAR-T therapies, which are designed to be safer, faster, and more scalable and accessible, aiming to address significant unmet needs in the treatment of relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL).

Average Trading Volume: 192,875

Technical Sentiment Signal: Buy

Current Market Cap: $342.9M

For detailed information about CLLS stock, go to TipRanks’ Stock Analysis page.

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