AstraZeneca ((AZN)), AstraZeneca plc ((GB:AZN)), AstraZeneca ((DE:ZEGA)), AstraZeneca plc US ((AZNCF)) announced an update on their ongoing clinical study.
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AstraZeneca is currently conducting a Phase 3 clinical study titled ‘DESTINY-Biliary Tract Cancer-01’ to evaluate the efficacy and safety of Trastuzumab Deruxtecan (T-DXd) and Rilvegostomig compared to the standard-of-care treatments in patients with advanced HER2-expressing biliary tract cancer. The study aims to assess whether these experimental therapies can offer better outcomes than the existing standard treatments of gemcitabine, cisplatin, and durvalumab.
The interventions being tested include Trastuzumab Deruxtecan and Rilvegostomig, both administered via intravenous infusion. These experimental drugs are designed to target HER2-expressing cancer cells, potentially offering a more effective treatment option for patients.
The study follows an interventional design with randomized allocation and a parallel intervention model. It is an open-label study, meaning both the researchers and participants know which treatment is being administered. The primary purpose of the study is treatment-focused.
The study officially began on August 12, 2024, with the latest update submitted on August 18, 2025. These dates are crucial as they mark the progress and ongoing status of the study, providing investors with a timeline for potential results and developments.
This clinical study update could significantly impact AstraZeneca’s stock performance, as successful results may enhance the company’s portfolio in oncology treatments, potentially increasing investor confidence. In the competitive landscape of cancer therapies, positive outcomes could position AstraZeneca favorably against its competitors.
The study is currently recruiting, with further details available on the ClinicalTrials portal.