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Alnylam Pharmaceuticals Reports Strong Q1 2025 Growth

Alnylam Pharmaceuticals ( (ALNY) ) has released its Q1 earnings. Here is a breakdown of the information Alnylam Pharmaceuticals presented to its investors.

Alnylam Pharmaceuticals is a leading biotechnology company specializing in RNA interference (RNAi) therapeutics, focusing on developing innovative medicines for rare and prevalent diseases. The company is renowned for its pioneering work in RNAi, a groundbreaking approach in gene silencing.

In the first quarter of 2025, Alnylam Pharmaceuticals reported significant financial growth, achieving global net product revenues of $469 million, marking a 28% increase from the previous year. This growth was primarily driven by the strong performance of its hATTR-PN franchise. Additionally, the company received FDA approval for AMVUTTRA, a treatment for ATTR-CM, and launched Qfitlia, a groundbreaking therapy for hemophilia.

Key financial highlights include a 36% increase in net product revenues for AMVUTTRA and ONPATTRO, and an 8% growth for GIVLAARI and OXLUMO. The company also reported a 20% increase in total revenues compared to the previous year. Despite a GAAP net loss, Alnylam showed a significant improvement in non-GAAP income from operations, reflecting its strategic focus on expanding its RNAi platform and pipeline.

Alnylam’s strategic advancements include the initiation of new clinical programs and the expansion of its neuroscience franchise. The company also presented promising data from its HELIOS-B Phase 3 clinical trial, supporting the efficacy of vutrisiran in treating ATTR-CM. Looking ahead, Alnylam plans to initiate several clinical trials and anticipates regulatory approvals in key markets.

Looking forward, Alnylam Pharmaceuticals remains optimistic about its growth prospects, reiterating its 2025 financial guidance. The company aims to achieve profitability through continued innovation and expansion of its RNAi platform, positioning itself as a leader in the biotechnology sector.

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