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Opaleye Management Inc. Insider Profile

67 Followers
Opaleye Management Inc., Ten Percent Owner at Grace Therapeutics, holds 2.78M shares in Grace Therapeutics (Ticker: GRCE), holds 551.88K shares in Sol-Gel Technologies (Ticker: SLGL), holds 3.15M shares in Alpha Cognition Inc (Ticker: ACOG). Most recently, Opaleye Management Inc. Bought ― shares of Grace Therapeutics on Sep 10, 2026 for an estimated value of $31.77K.
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Opaleye Management Inc.

Opaleye Management Inc.
Grace Therapeutics (GRCE)
Ten Percent Owner

Ranked #1,336 out of 109,030 Corporate Insiders

Profitable Transactions

45%
89 out of 197 Profitable Transactions

Average Return

+14.00%
Average return per transaction
Time Frame
1 Year
Compare to
No Benchmark

Insider Holdings

$434M
35.61%
29.27%
12.39%
8.39%
14.33% Others
A breakdown of Opaleye Management Inc.'s holdings

Insider Roles

Eton Pharmaceuticals
(ETON)
Ten Percent Owner
Harrow Health
(HROW)
Ten Percent Owner
Ocular Therapeutix
(OCUL)
Previously a 10% owner
Sol-Gel Technologies
(SLGL)
Ten Percent Owner
+6 other positions
Roles that Opaleye Management Inc. holds in companies

Most Profitable Insider Trade

Stock:
Ocular Therapeutix
(OCUL)
Rating:Informative Buy
Date:Jan 02, 2020 - Jan 02, 2021
Return:+424.00%
The most profitable trade made by Opaleye Management Inc.

Opaleye Management Inc.'s Trading History

Company Name
Last Transaction Date
Insider Position
Last Transaction
Last Transaction Amount
Holding Value
Grace Therapeutics
Sep 10, 2026
Ten Percent Owner
Informative Buy
31.77K
$6.16M
Harrow Health
Mar 05, 2026
Ten Percent Owner
Informative Sell
7.85M
$126.94M
Ocular Therapeutix
Jan 03, 2020
Previously a 10% owner
Informative Buy
58.50K
$53.74M
TCON
TRACON Pharmaceuticals
Nov 14, 2023
Informative Sell
1.38M
$0.00
Protara Therapeutics
Sep 12, 2024
Ten Percent Owner
Informative Sell
270.46K
$7.60M
Eton Pharmaceuticals
Jul 16, 2026
Ten Percent Owner
Informative Sell
1.06M
$154.40M
TELA Bio
Nov 04, 2022
Former 10% Owner.
Informative Buy
158.25K
$2.01M
Codexis
Dec 01, 2025
Ten Percent Owner
Informative Sell
617.67K
$14.85M
Sanuwave Health
May 04, 2026
Ten Percent Owner
Informative Sell
574.21K
$3.52M
Sol-Gel Technologies
Sep 09, 2026
Ten Percent Owner
Informative Buy
687.14K
$36.39M
Alpha Cognition Inc
Aug 04, 2026
Ten Percent Owner
Informative Buy
422.97K
$28.02M
List of latest transactions for each holding click on a transaction to see Opaleye Management Inc.'s performance on stock

Opaleye Management Inc. insider profile FAQ

What is the percentage of profitable transactions made by Opaleye Management Inc.?
The percentage of profitable transactions made by Opaleye Management Inc. is 45%.
    What is the average return per transaction made by Opaleye Management Inc.?
    The average return per transaction made by Opaleye Management Inc. is 14.00%.
      What stocks does Opaleye Management Inc. hold?
      Opaleye Management Inc. holds: GRCE, HROW, OCUL, TCON, TARA, ETON, TELA, CDXS, SNWV, SLGL, ACOG stocks.
        What was Opaleye Management Inc.’s latest transaction?
        Opaleye Management Inc. latest transaction was an Informative Buy of $31.77K.
          What was Opaleye Management Inc.'s most profitable transaction?
          Opaleye Management Inc.’s most profitable transaction was an Informative Buy of OCUL stock on January 2, 2020. The return on the trade was 424.00%.
            What is Opaleye Management Inc.'s role in Grace Therapeutics?
            Opaleye Management Inc.'s role in Grace Therapeutics is Ten Percent Owner.
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