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SPDR S&P BIOTECH ETF
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XBI Holdings Information

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Last updated: September 1, 2026

Holdings Count
148
Total Assets
11.41B
Top 10 Percentage
15.71%
Asset Class
Equity
Category
Sector
Region
North America
See the full list of holdings, find out what stocks are the most undervalued and get access to the all ETF's smart score and filters.Go Premium

Top Holdings

148 Holdings as of Sep 01, 2026
148 Holdings as of Sep 01, 2026
Name
Weight %
Market Value
Price & Change
Market Cap
Yearly Gain
Analyst Consensus
Analyst Price Target
Smart Score
Follow
MRNA
Moderna
2.82%$320.05M―$56.03B537.74%
3 Buy
13 Hold
1 Sell
Hold
―
TWST
Twist Bioscience
1.90%$215.11M―$9.15B403.28%
8 Buy
1 Hold
0 Sell
Strong Buy
―
APGE
Apogee Therapeutics, Inc.
1.51%$171.27M―$10.22B256.79%
3 Buy
12 Hold
0 Sell
Hold
―
KYMR
Kymera Therapeutics, Inc.
1.40%$159.29M―$9.88B192.58%
16 Buy
2 Hold
0 Sell
Strong Buy
―
HALO
Halozyme Therapeutics
1.40%$158.44M―$12.09B46.88%
5 Buy
1 Hold
1 Sell
Moderate Buy
―
NTRA
Natera Inc.
1.37%$155.98M―$46.41B89.42%
18 Buy
2 Hold
0 Sell
Strong Buy
―
PRAX
Praxis Precision Medicines, Inc.
1.35%$152.65M―$9.78B686.47%
15 Buy
1 Hold
0 Sell
Strong Buy
―
ORKA
Oruka Therapeutics, Inc.
1.34%$151.71M―$6.13B491.97%
11 Buy
0 Hold
0 Sell
Strong Buy
―
RVMD
Revolution Medicines, Inc.
1.32%$149.52M―$44.06B430.91%
20 Buy
1 Hold
0 Sell
Strong Buy
―
TVTX
Travere Therapeutics, Inc.
1.31%$148.74M―$6.25B262.04%
11 Buy
1 Hold
0 Sell
Strong Buy
―
Rows:
10

Sector Breakdown

89.88%Healthcare10.12%General89.88%Healthcare
Healthcare
89.88%
General
10.12%

Countries Breakdown

100.00%United States100.00%United States
United States
100.00%

Breakdown By Smart Score

14.25%Outperform1015.78%Outperform913.18%Outperform825.60%Neutral715.73%Neutral65.45%Neutral55.42%Neutral40.56%Underperform32.70%Underperform21.33%Underperform17
The weighted average smart score of the XBI ETF is 7
10
14.25%
9
15.78%
8
13.18%
7
25.60%
6
15.73%
5
5.45%
4
5.42%
3
0.56%
2
2.70%
1
1.33%

XBI ETF News

See More XBI News
See More XBI News

XBI ETF FAQ

What are ETF XBI’s top 3 holdings?
XBI’s top 3 holdings are MRNA, TWST, APGE.
    What is XBI’s holding count?
    ETF XBI’s is holdings 148 different assets.
      What are the total assets of ETF XBI?
      ETF XBI’s total assets are 11.41B.
        What sector is XBI most exposed to?
        XBI is most exposed to 89.88% Healthcare of its holdings.
          How concentrated is XBI?
          XBI’s top 10 holdings represent 15.71% of the fund.
            What is XBI’s average Smart Score?
            The weighted average Smart Score of XBI is 7.
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