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111 (YI) AI Stock Analysis

YI

111

(NASDAQ:YI)

Select Model
Rating:39Underperform
Price Target:$2.50â–¼(-16.39% Downside)
Action:reiterated
Date:09/29/26

Primarily impacted by poor financial performance due to declining revenues and negative equity. Mixed technical indicators and unattractive valuation further weigh on the score.

Positive Factors
Asset-Light AI StrategyThe shift toward an asset-light, AI-powered platform can improve operating scalability by reducing fulfillment intensity and administrative costs. If execution continues, technology-enabled efficiency may support a leaner cost structure and strengthen the company’s ability to serve healthcare partners over the next several quarters.
Negative Factors
Contracting RevenueThe substantial revenue decline shows that the strategic reshaping is reducing the current scale of the business, even if some divestitures improve quality. A smaller revenue base can constrain operating leverage and makes future growth dependent on successfully replacing exited activity with platform revenue.

111 (YI) vs. SPDR S&P 500 ETF (SPY)

-50%-25%0%25%50%75%100%YI-32.87%SPY+12.58%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
$25.65M
Dividend Yield
―
Average Volume (3M)
14.44K
Price to Earnings (P/E)
-1.6
Beta (1Y)
0.76
Revenue Growth
-23.90%
EPS Growth
-45.45%
Country
US
Employees
1,063
Sector
Healthcare
Sector Strength
51
Industry
Medical - Distribution

111 Business Overview & Revenue Model

Company Description

Based in Shanghai, People's Republic of China, 111, Inc. (established in 2010 and formerly known as New Peak Group until April 2018) is a prominent entity in the Chinese healthcare sector, operating a comprehensive online-to-offline (O2O) ecosystem....

How the Company Makes Money

111, Inc. primarily makes money by facilitating and fulfilling the sale of pharmaceuticals and other healthcare products through its digital healthcare platform and related distribution operations. Its revenue model is centered on: (1) product sales...

111 Earnings Call Summary

Earnings Call Date:Mar 19, 2025(Q4-2024)|% Change Since:-72.82%|Next Earnings Date:Jun 03, 2026
Earnings Call SentimentPositive

The earnings call demonstrates significant achievements in operational profitability and cost reduction despite challenging macroeconomic conditions and regulatory changes. The company's advancements in technology and supply chain expansion position it well for future growth, though market and competitive pressures remain.

Positive Updates

First Ever Operational Profitability
111 achieved its first ever operational profitability and positive operating cash flow in 2024, marking a significant milestone in the company's history.

Negative Updates

Macroeconomic Challenges in China
Economic uncertainties and healthcare reforms in China have led to cautious consumer behavior, affecting retail sales and healthcare expenditure growth.

Company Guidance

During the conference call held on March 20, 2025, the management of 111 provided insights into their fiscal year 2024 performance and future outlook. Despite macroeconomic challenges and healthcare reforms impacting the industry, 111 achieved its first-ever operational profitability and positive operating cash flow. The company reduced operating expenses by 31% year-over-year, bringing them down to 5.7% of revenues. Key financial highlights included a yearly profit from operations of RMB2.1 million, a turnaround from a RMB350.1 million operational loss in 2023, and a non-GAAP income from operations of RMB22.3 million. The company also highlighted advancements in technology and supply chain infrastructure, such as their decentralized inventory network and AI-driven demand forecasting, which significantly improved operational efficiency. Looking ahead, 111 plans to leverage AI and digital transformation to enhance customer engagement and operational efficiency, aiming to capitalize on China's evolving healthcare market and structural trends like the aging population and healthcare transparency reforms.

111 Financial Statement Overview

Summary

Revenue decline, negative equity, and inconsistent cash flows signal significant financial distress.

Income Statement

23Negative

Balance Sheet

12Very Negative

Cash Flow

32Negative
Financial statement breakdown
BreakdownTTMMar 2026Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue10.44B12.21B14.40B14.95B13.52B12.43B
Gross Profit598.89M703.70M829.23M848.98M839.98M621.10M
EBITDA-28.91M1.81M24.62M-311.26M-321.81M-588.32M
Net Income-95.03M-16.84M-64.74M-392.69M-416.88M-669.81M
Balance Sheet
Total Assets1.79B2.20B2.79B3.09B3.47B3.15B
Cash, Cash Equivalents and Short-Term Investments381.26M611.72M462.29M653.67M879.53M843.95M
Total Debt281.98M217.73M256.77M443.23M344.19M491.01M
Total Liabilities1.63B1.99B2.41B2.81B2.83B2.30B
Stockholders Equity-114.41M-702.68M-642.64M-583.45M-414.60M-173.32M
Cash Flow
Free Cash Flow-39.66M114.69M247.82M-457.07M-54.73M-751.53M
Operating Cash Flow-35.20M119.14M263.02M-447.24M-23.15M-688.84M
Investing Cash Flow-63.92M-53.72M37.38M151.74M-47.17M60.14M
Financing Cash Flow-91.81M-21.19M-406.24M205.98M22.73M74.34M

111 Technical Analysis

Technical Analysis SentimentNegative
Last Price2.99

Price Trends

50DMA3.31Negative
100DMA3.63Negative
200DMA5.06Negative

Market Momentum

MACD-0.12Positive
RSI32.65Neutral
STOCH32.84Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For YI, the sentiment is Negative. The current price of 2.99 is below the 20-day moving average (MA) of 3.07, below the 50-day MA of 3.31, and below the 200-day MA of 5.06, indicating a bearish trend. The MACD of -0.12 indicates Positive momentum. The RSI at 32.65 is Neutral, neither overbought nor oversold. The STOCH value of 32.84 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for YI.

111 Risk Analysis

111 disclosed 83 risk factors in its most recent earnings report. 111 reported the most risks in the "Finance & Corporate" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy

Latest Risks Added

3 New Risks
1.If the PCAOB is prevented from fully evaluating audits and quality control procedures of our auditor, investors may be deprived of the benefits of such PCAOB inspections.Q4, 2023
2.It may be difficult for regulators to conduct cross-border investigation.Q4, 2023
3.An outbreak of disease or similar public health threat, or fear of such an event, could have a material adverse impact on our business, operating results and financial conditionQ4, 2023

111 Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

YI against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
RMTIRMTI60Neutral$28.50M-4.97-14.03%―-21.12%-109.07%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
NEUPNEUP48Neutral$16.50M-0.42-77.03%―――
ELUTELUT40Underperform$37.07M0.63940.81%―-48.76%-3.02%
YIYI39Underperform$25.04M-1.6323.64%―-23.90%-45.45%
DYAIDYAI39Underperform$15.23M-1.76-2918.10%―-8.05%-14.12%
RNTXRNTX32Underperform$57.80M-0.35-234.45%――36.23%

* Healthcare Sector Average

Performance Comparison

-50%0%50%YIRMTIDYAIRNTXELUTNEUPDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
YI and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
YI111, Inc.2.92-1.52-34.23%
RMTIRockwell Medical6.91-3.49-33.56%
DYAIDyadic International Inc.0.38-0.67-64.19%
RNTXRein Therapeutics, Inc0.64-0.78-55.28%
ELUTElutia Inc.0.82-0.10-10.76%
NEUPNeuphoria Therapeutics Inc.3.04-1.18-27.96%

111 Corporate Events

111, Inc. Forms Special Committee Advisers to Review September Take-Private Proposal

Oct 26, 2026

On October 26, 2026, Shanghai-based 111, Inc. said a special committee of three independent directors formed by its board has hired Houlihan Lokey China Limited as independent financial advisor and Kirkland & Ellis as U.S. legal counsel. The mand...

111, Inc. Forms Special Committee to Review Buyout Proposal and Strategic Alternatives

Sep 28, 2026

111, Inc., a Shanghai-based technology-enabled healthcare platform listed on Nasdaq, operates consumer-facing 1 Pharmacy and B2B-focused 1 Medicine, using digital tools and AI to connect consumers, pharmacies and pharmaceutical companies across China...

111, Inc. Co-Founders Lead Unsolicited Bid to Take Nasdaq-Listed Healthcare Platform Private

Sep 17, 2026

On September 17, 2026, 111, Inc. disclosed that its board had received an unsolicited preliminary non-binding proposal dated September 16 from a buyer group led by co-founders Gang Yu and CEO Junling Liu, together with Huadeng Tech BioArray Ventures....

111, Inc. Posts Q2 2026 Results as Asset-Light, AI-Driven Healthcare Platform Strategy Advances

Sep 17, 2026

In the second quarter of 2026, 111, Inc. reported net revenue of RMB2.3 billion, down 28.3% year over year, largely due to the deliberate divestiture of underperforming subsidiaries as it pivots to an asset-light, platform-oriented model. Despite the...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Sep 29, 2026