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Open Orphan Plc (OPORF)
OTHER OTC:OPORF

Open Orphan Plc (OPORF) Price & Analysis

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OPORF Stock Chart & Stats

$0.11
$0.02(27.29%)
At close: 4:00 PM EDT
$0.11
$0.02(27.29%)

Bulls Say, Bears Say

Bulls Say
Record Order BookA record order book and rising proposal activity indicate a substantial contracted and prospective demand base. Management says the backlog provides visibility through 2026 and into 2027-2028, supporting capacity utilization and multi-period revenue planning despite timing shifts.
Specialist Competitive PositionThe dedicated facilities, volunteer database and infectious-disease expertise support delivery of challenge-trial data in about 12 months, which management describes as roughly 3.5 times faster than natural-infection studies. This combination can reinforce differentiation and customer value.
Accretive Strategic AcquisitionCRS Berlin broadens the platform with profitable, cash-generative clinical capacity and is expected to contribute revenue and EBITDA immediately. Its dermatology and women's health capabilities, larger bed base and patient catchment also expand Open Orphan's addressable market.
Bears Say
Revenue Execution DelaysThe revenue decline shows that contract timing remains a material execution constraint even when projects are deferred rather than canceled. Shifting challenge-trial work across reporting periods reduces near-term utilization, delays cash conversion and makes revenue planning less predictable.
Persistent Losses And Cash BurnOngoing EBITDA losses combined with a projected reduction in cash leave less internal funding for operations and growth. The expected year-end cash decline increases reliance on successful delivery and collection of contracted work, while limiting flexibility if recovery is delayed.
Margin UncertaintyLower-margin clinical-services work and limited visibility on a normalized margin make future earnings quality difficult to assess. Even with revenue recovery, mix changes and higher general and administrative costs could constrain operating leverage and delay a durable return to profitability.

Open Orphan Plc News

OPORF FAQ

What was Open Orphan Plc’s price range in the past 12 months?
Open Orphan Plc lowest stock price was $0.09 and its highest was $0.24 in the past 12 months.
    What is Open Orphan Plc’s market cap?
    Open Orphan Plc’s market cap is $54.73M.
      When is Open Orphan Plc’s upcoming earnings report date?
      Open Orphan Plc’s upcoming earnings report date is Apr 14, 2027 which is in 183 days.
        How were Open Orphan Plc’s earnings last quarter?
        Open Orphan Plc released its earnings results on Sep 15, 2026. The company reported -$0.011 earnings per share for the quarter.
          Is Open Orphan Plc overvalued?
          According to Wall Street analysts Open Orphan Plc’s price is currently Overvalued. Get more investment ideas with TipRanks Premium
            Does Open Orphan Plc pay dividends?
            Open Orphan Plc pays a Annually dividend of $0.003 which represents an annual dividend yield of 2.36%. See more information on Open Orphan Plc dividends here
              What is Open Orphan Plc’s EPS estimate?
              Open Orphan Plc’s EPS estimate for its next earnings report is not yet available.
              How many shares outstanding does Open Orphan Plc have?
              Open Orphan Plc has 688,401,060 shares outstanding.
                What happened to Open Orphan Plc’s price movement after its last earnings report?
                Open Orphan Plc reported an EPS of -$0.011 in its last earnings report. Following the earnings report the stock price went same 0%.
                  Which hedge fund is a major shareholder of Open Orphan Plc?
                  Currently, no hedge funds are holding shares in OPORF
                  What is the TipRanks Smart Score and how is it calculated?
                  Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology

                    Open Orphan Plc Stock Smart Score

                    3
                    Underperform
                    1
                    2
                    3
                    4
                    5
                    6
                    7
                    8
                    9
                    10

                    Technicals

                    SMA
                    Negative
                    20 days / 200 days
                    Momentum
                    -7.69%
                    12-Months-Change

                    Fundamentals

                    Return on Equity
                    -35.13%
                    Trailing 12-Months
                    Asset Growth
                    -14.64%
                    Trailing 12-Months
                    Learn more about TipRanks Smart Score

                    Company Description

                    Open Orphan Plc

                    hVIVO plc (HVO) operates as a premier full-service Contract Research Organisation (CRO) focused on early-phase clinical development, globally recognized as the leader in human challenge trials. The company provides a complete spectrum of clinical development services to a wide-ranging and growing client base, which includes seven of the world's ten largest biopharmaceutical companies. A key specialisation for hVIVO is orchestrating human challenge trials across numerous infectious and respiratory diseases, utilising its advanced, London-based quarantine facility, the largest of its kind globally. Additionally, the company offers extensive virology and immunology laboratory services through its hLAB division. Through its German subsidiary, CRS, hVIVO manages a 120-bed capacity across sites in Mannheim and Kiel, delivering early-phase clinical trial expertise, including first-in-human and proof-of-concept studies. Its other subsidiary, Venn Life Sciences, contributes to the biopharma sector by providing specialist early drug development consulting and biometry services. The Group collectively offers integrated drug development solutions, covering stages from preclinical research up to Phase II trials, supported by patient recruitment via FluCamp. Moreover, its five clinical sites facilitate outpatient Phase II and III trials, ensuring a streamlined and effective transition from drug discovery to late-stage development.

                    Open Orphan Plc (OPORF) Earnings & Revenues

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                    Ownership Overview

                    1.68%98.28%
                    ― Other Institutional Investors
                    98.28% Public Companies and
                    Individual Investors
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