Ultragenyx Pharmaceutical stock analysis
Ultragenyx Pharmaceutical (RARE) Stock Price & Analysis
RARE Stock Chart & Stats
- Day’s Range
- MXN 256.00 - MXN 256.00
- 52-Week Range
- MXN 240.00 - MXN 811.00
- Previous Close
- MXN 256.00
- Volume
- 0
- Average Volume (3M)
- 1
- Market Cap
- MXN 29.14B
- Enterprise Value
- MXN 2.45B
- Total Cash (Recent Filing)
- MXN 266.00M
- Total Debt (Recent Filing)
- MXN 1.19B
- Price to Earnings (P/E)
- ―
- Beta
- 0.14
- Next Earnings
- Feb 18, 2027 (Est.)
- EPS Estimate
- 40.81
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Revenue Growth And Gross Margin
Strong revenue momentum combined with very high gross margins indicates improving commercial traction and attractive product economics. If sustained, this profile can provide increasing resources to fund launches, support selective pipeline investment, and strengthen the company’s ability to approach profitability.
Expanded Rare-Disease Franchise
Reaching six approved medicines broadens Ultragenyx’s commercial platform and adds two gene therapies to its rare-disease franchise. Multiple products and specialized treatment expertise can support durable growth, improve market reach, and reduce reliance on a single development outcome.
Nondilutive Funding And Profitability Plan
The expected $350 million of nondilutive PRV proceeds improves funding flexibility without an equity raise, while management’s 2027 plan targets lower R&D, positive operating cash flow, and GAAP profitability. Execution would materially improve self-funding capacity and financial resilience.
Bears Say
Persistent Losses And Cash Burn
Large negative operating and free cash flow show that the business has not yet converted commercial growth into internal funding. Continued cash consumption can constrain investment choices and increase dependence on successful launches, cost reductions, or additional capital before profitability is achieved.
Negative Equity And Balance-Sheet Risk
Negative equity reflects accumulated losses that have more than offset invested capital, weakening financial flexibility. The differing debt figures across periods add uncertainty to the capital structure, while the combination increases sensitivity to execution setbacks until sustained profits rebuild the balance sheet.
Pipeline Setbacks And Portfolio Reduction
The GTX-102 failure and UX701 termination reduce late-stage pipeline breadth and remove potential future growth drivers. Workforce and portfolio reductions may improve efficiency, but they also signal narrower development capacity and leave future expansion more dependent on existing products and new launches.
Ultragenyx Pharmaceutical News
Ultragenyx’s GTX-102 Angelman Syndrome Study Terminated: What Investors Should Know
Ultragenyx Pharmaceutical, Inc. ($RARE) announced an update on their ongoing clinical study. Study Overview: Ultragenyx’s Phase 3 study, officially titled “A Phase 3, Randomized, Double-blind, Sham-controlled Study Investigating the Efficacy
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Ultragenyx Pharmaceutical Stock Smart Score
Company Description
Ultragenyx Pharmaceutical
Ultragenyx Pharmaceutical Inc. is a biopharmaceutical firm dedicated to discovering, developing, and commercializing innovative treatments for rare and ultra-rare genetic conditions. Its operations span North America, Europe, and other international markets. The company's portfolio of marketed biologic products addresses several serious diseases. This includes Crysvita (burosumab), an antibody that targets fibroblast growth factor 23, used to treat X-linked hypophosphatemia and tumor-induced osteomalacia. Mepsevii offers enzyme replacement therapy for both pediatric and adult patients suffering from Mucopolysaccharidosis VII. Dojolvi is available for individuals with long-chain fatty acid oxidation disorders, while Evkeeza (evinacumab) provides a treatment option for homozygous familial hypercholesterolemia. Ultragenyx also boasts a robust pipeline of investigational therapies. Notable candidates include DTX401, an adeno-associated virus 8 (AAV8) gene therapy for glycogen storage disease type Ia, and DTX301, another AAV8 gene therapy aimed at ornithine transcarbamylase deficiency. Other promising developments feature UX143, a human monoclonal antibody for osteogenesis imperfecta; GTX-102, an antisense oligonucleotide designed for Angelman syndrome; UX701, targeting Wilson disease; and UX053, in development for glycogen storage disease type III. To advance its research and development efforts, Ultragenyx Pharmaceutical Inc. maintains strategic collaboration and licensing agreements with numerous partners, such as Kyowa Kirin Co., Ltd., Saint Louis University, REGENXBIO Inc., Bayer Healthcare LLC, GeneTx, Mereo, University of Pennsylvania, Arcturus Therapeutics Holdings Inc., Solid Biosciences Inc., and Daiichi Sankyo Co., Ltd. The company was founded in 2010 and operates from its headquarters in Novato, California.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Emil D. Kakkis
- Employees
- 1,371
- Website
- www.ultragenyx.com
- Address
- 60 Leveroni Court, Novato, CA, 94949, US
Ultragenyx Pharmaceutical (RARE) Earnings & Revenues
RARE Earnings Call
Earnings Call SentimentNeutral
The call had substantial positive developments, including two first-ever gene therapy approvals, strong demand and launch preparation, growth across established products, approximately $350 million in nondilutive proceeds, and reaffirmed 2027 profitability expectations. These were balanced by the GTX-102 Phase 3 failure, termination of UX701, a roughly 20% workforce reduction, restructuring charges, and uncertainty around the setrusumab regulatory path. Overall sentiment was mixed and balanced.
View all MX:RARE earnings summariesRARE Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 4 | 2 | 11 |
| Technical Analysis | 2 | 1 | 2 |
| Moving Averages | 2 | 1 | 9 |











