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Ionis Pharmaceuticals (MX:IONS)
:IONS
Mexico Market
IONS
Ionis Pharmaceuticals
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Ionis Pharmaceuticals (IONS) Ratios

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Ionis Pharmaceuticals Ratios

MX:IONS's free cash flow for Q2 2026 was $0.99. For the 2026 fiscal year, MX:IONS's free cash flow was decreased by $ and operating cash flow was $-0.41. See a summary of the company’s cash flow.
Ratios
TTM
Dec 25Dec 24Dec 23Dec 22
Liquidity Ratios
Current Ratio
 7.88 3.83 8.47 5.90 7.07
Quick Ratio
 7.72 3.81 8.43 5.88 7.00
Cash Ratio
 1.11 0.48 0.78 0.89 0.89
Solvency Ratio
 1.67 -0.12 -0.18 -0.13 -0.13
Operating Cash Flow Ratio
 -1.57 -0.34 -1.62 -0.69 -0.88
Short-Term Operating Cash Flow Coverage
 -2.05 -0.59 -53.99 -5.78 -36.41
Net Current Asset Value
$ -64.20M$ -44.75M$ 204.97M$ 38.47M$ 241.71M
Leverage Ratios
Debt-to-Assets Ratio
 0.81 0.74 0.47 0.49 0.54
Debt-to-Equity Ratio
 5.50 5.35 2.41 3.76 2.39
Debt-to-Capital Ratio
 0.85 0.84 0.71 0.79 0.71
Long-Term Debt-to-Capital Ratio
 0.81 0.80 0.68 0.76 0.67
Financial Leverage Ratio
 6.81 7.20 5.11 7.73 4.42
Debt Service Coverage Ratio
 13.06 -0.53 -3.48 -1.99 -15.30
Interest Coverage Ratio
 -6.65 -4.22 -5.25 -4.34 -50.50
Debt to Market Cap
 0.22 0.19 0.24 0.18 0.22
Interest Debt Per Share
 15.16 16.91 10.08 10.73 9.71
Net Debt to EBITDA
 0.48 -7.82 -3.32 -4.47 -4.80
Profitability Margins
Gross Profit Margin
98.16%98.31%98.41%98.84%97.60%
EBIT Margin
-57.44%-32.52%-53.28%-32.80%-42.54%
EBITDA Margin
495.59%-30.38%-50.16%-29.95%-38.78%
Operating Profit Margin
-68.09%-40.47%-67.37%-44.91%-69.84%
Pretax Profit Margin
-64.33%-40.25%-65.25%-42.40%-43.92%
Net Profit Margin
-64.64%-40.36%-64.37%-46.50%-45.92%
Continuous Operations Profit Margin
-64.35%-40.36%-64.37%-46.50%-45.92%
Net Income Per EBT
100.48%100.26%98.66%109.68%104.55%
EBT Per EBIT
94.48%99.48%96.84%94.41%62.89%
Return on Assets (ROA)
-18.86%-10.81%-15.11%-12.25%-10.64%
Return on Equity (ROE)
-110.84%-77.90%-77.15%-94.72%-47.08%
Return on Capital Employed (ROCE)
-22.21%-13.93%-17.63%-13.92%-18.46%
Return on Invested Capital (ROIC)
-20.37%-11.96%-17.34%-13.63%-18.40%
Return on Tangible Assets
-18.86%-10.81%-15.11%-12.25%-10.64%
Earnings Yield
-5.88%-3.01%-8.68%-5.06%-5.03%
Efficiency Ratios
Receivables Turnover
 14.85 14.30 7.65 8.06 23.00
Payables Turnover
 0.34 0.57 0.26 0.35 0.79
Inventory Turnover
 0.32 1.59 0.90 1.23 0.64
Fixed Asset Turnover
 2.26 2.61 2.75 3.24 2.30
Asset Turnover
 0.29 0.27 0.23 0.26 0.23
Working Capital Turnover Ratio
 0.40 0.42 0.31 0.39 0.29
Cash Conversion Cycle
 95.70 -385.88 -943.36 -697.48 122.19
Days of Sales Outstanding
 24.58 25.52 47.72 45.31 15.87
Days of Inventory Outstanding
 1.16K 229.22 407.21 297.38 569.71
Days of Payables Outstanding
 1.08K 640.62 1.40K 1.04K 463.39
Operating Cycle
 1.18K 254.74 454.93 342.69 585.58
Cash Flow Ratios
Operating Cash Flow Per Share
 -3.00 -1.68 -3.35 -2.15 -1.93
Free Cash Flow Per Share
 -3.38 -2.00 -3.65 -2.35 -2.08
CapEx Per Share
 0.38 0.32 0.30 0.20 0.14
Free Cash Flow to Operating Cash Flow
 1.13 1.19 1.09 1.09 1.07
Dividend Paid and CapEx Coverage Ratio
 -7.95 -5.22 -11.06 -10.98 -13.65
Capital Expenditure Coverage Ratio
 -7.95 -5.22 -11.06 -10.98 -13.65
Operating Cash Flow Coverage Ratio
 -0.21 -0.10 -0.35 -0.21 -0.20
Operating Cash Flow to Sales Ratio
 -0.57 -0.28 -0.71 -0.39 -0.47
Free Cash Flow Yield
-5.79%-2.53%-10.45%-4.64%-5.50%
Valuation Ratios
Price-to-Earnings (P/E) Ratio
 -16.79 -33.24 -11.50 -19.75 -19.86
Price-to-Sales (P/S) Ratio
 11.05 13.41 7.41 9.18 9.12
Price-to-Book (P/B) Ratio
 21.85 25.88 8.88 18.71 9.35
Price-to-Free Cash Flow (P/FCF) Ratio
 -17.27 -39.55 -9.57 -21.56 -18.19
Price-to-Operating Cash Flow Ratio
 -19.36 -47.13 -10.43 -23.53 -19.53
Price-to-Earnings Growth (PEG) Ratio
 0.20 1.53 -0.61 -0.57 -0.02
Price-to-Fair Value
 21.85 25.88 8.88 18.71 9.35
Enterprise Value Multiple
 2.71 -51.96 -18.10 -35.14 -28.32
Enterprise Value
 11.72B 14.90B 6.40B 8.29B 6.45B
EV to EBITDA
 2.71 -51.96 -18.10 -35.14 -28.32
EV to Sales
 13.42 15.78 9.08 10.52 10.98
EV to Free Cash Flow
 -20.97 -46.56 -11.72 -24.70 -21.90
EV to Operating Cash Flow
 -23.61 -55.48 -12.78 -26.95 -23.51
Tangible Book Value Per Share
 2.65 3.06 3.94 2.70 4.04
Shareholders’ Equity Per Share
 2.66 3.06 3.94 2.70 4.04
Tax and Other Ratios
Effective Tax Rate
 >-0.01 >-0.01 0.01 -0.10 -0.05
Revenue Per Share
 5.28 5.90 4.72 5.51 4.14
Net Income Per Share
 -3.41 -2.38 -3.04 -2.56 -1.90
Tax Burden
 1.00 1.00 0.99 1.10 1.05
Interest Burden
 1.12 1.24 1.22 1.29 1.03
Research & Development to Revenue
 1.06 0.97 1.28 1.14 1.42
SG&A to Revenue
 0.60 0.42 0.38 0.30 0.26
Stock-Based Compensation to Revenue
 0.14 0.14 0.18 0.13 0.17
Income Quality
 0.88 0.70 1.10 0.84 1.02
Currency in USD