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Matinas BioPharma (MTNB) AI Stock Analysis

MTNB

Matinas BioPharma

(NYSE MKT:MTNB)

Select Model
Rating:37Underperform
Price Target:$1.50â–¼(-0.66% Downside)
Action:reiterated
Date:10/20/26

Matinas BioPharma receives the lowest possible score due to extreme fundamental and technical distress. The primary risks include a severely depleted balance sheet, significant solvency concerns, and an active NYSE delisting notice. Paired with a persistent technical downtrend, lack of revenue, and heavy reliance on external capital, the stock presents a highly precarious profile.

Positive Factors
Minimal LeverageMinimal debt reduces fixed financial obligations and near-term solvency pressure, giving Matinas more flexibility than a highly leveraged biotech. This low leverage can help preserve strategic options while the company develops its platform and seeks a sustainable funding path.
Negative Factors
No Meaningful RevenueThe absence of meaningful revenue confirms that Matinas has not yet established a commercial operating base. Continued losses without product revenue leave financial performance dependent on development progress and external capital, limiting visibility into sustainable earnings power over the next several quarters.

Matinas BioPharma (MTNB) vs. SPDR S&P 500 ETF (SPY)

-100%-80%-60%-40%-20%0%20%MTNB-92.07%SPY+11.79%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
Market Cap
$644.89K
Dividend Yield
―
Average Volume (3M)
91.64K
Price to Earnings (P/E)
-0.1
Beta (1Y)
1.99
Revenue Growth
―
EPS Growth
68.91%
Country
US
Employees
2
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Matinas BioPharma Business Overview & Revenue Model

Company Description

Matinas BioPharma Holdings, Inc. is a biopharmaceutical firm in the clinical development phase, dedicated to identifying and advancing a range of potential therapeutic products. The company's innovative Lipid Nanocrystal (LNC) platform technology und...

Matinas BioPharma Earnings Call Summary

Earnings Call Date:Aug 13, 2024(Q2-2024)|% Change Since:-98.72%|Next Earnings Date:May 13, 2019
Earnings Call SentimentNeutral

The earnings call presented a mixed picture, with notable progress in MAT2203 licensing and financial management, counterbalanced by the lack of revenue, delays in trial timelines, and challenges in oncology trials. The sentiment is cautiously optimistic but acknowledges the hurdles that need addressing.

Positive Updates

MAT2203 Licensing Progress
Matinas BioPharma has signed a nonbinding term sheet for the licensing of global rights to develop, manufacture, and commercialize MAT2203, indicating potential future growth and collaborations.

Negative Updates

No Revenue Reported
The company did not report any revenue for the second quarter of 2024, similar to the same period in 2023.

Company Guidance

During the Matinas BioPharma Q2 2024 earnings call, several key metrics and guidance updates were provided. The company reported a net loss of $5.7 million or $0.02 per share for the quarter, a slight improvement from the $6.1 million or $0.03 per share loss in the same period of 2023. Total costs and expenses decreased to $5.8 million from $6.2 million year-over-year, primarily due to reduced clinical development and administrative costs. Matinas did not report any revenue for the quarter, consistent with the previous year. Cash, cash equivalents, and marketable securities stood at $14.3 million as of June 30, 2024, an increase from $13.8 million at the end of 2023, bolstered by $10 million in gross proceeds from a registered direct offering. The company is advancing plans for the ORALTO Phase III trial for MAT2203, with ongoing preparations and a potential start in the fourth quarter of 2024. Additionally, Matinas has signed a nonbinding term sheet for the global rights to develop, manufacture, and commercialize MAT2203, with the final agreement potentially including upfront payments, development and commercial milestones, and royalties.

Matinas BioPharma Financial Statement Overview

Summary

The company generates zero revenue and possesses a critically depleted asset base of just $3.4 million. Despite management successfully narrowing net losses, ongoing cash burn and minimal equity highlight severe solvency risks.

Income Statement

25Negative

Balance Sheet

15Very Negative

Cash Flow

20Very Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0001.10M3.19M33.00K
Gross Profit-107.00K-456.00K-972.00K155.00K-13.49M-14.55M
EBITDA-6.27M-9.89M-19.19M-22.00M-20.10M-22.50M
Net Income-7.31M-10.35M-24.25M-22.94M-21.00M-23.28M
Balance Sheet
Total Assets3.41M7.21M12.64M25.10M78.87M61.33M
Cash, Cash Equivalents and Short-Term Investments761.00K4.00M7.28M13.76M28.81M49.62M
Total Debt6,0001.35M2.89M3.56M4.12M4.70M
Total Liabilities1.61M2.38M5.05M5.86M42.23M8.83M
Stockholders Equity1.80M4.83M7.59M19.25M36.64M52.49M
Cash Flow
Free Cash Flow-6.42M-7.01M-15.88M-15.50M-20.05M-15.48M
Operating Cash Flow-6.42M-7.01M-15.88M-15.28M-19.16M-15.22M
Investing Cash Flow335.00K335.00K9.21M13.24M4.88M16.77M
Financing Cash Flow121.00K3.39M9.17M-7,00079.00K6.96M

Matinas BioPharma Technical Analysis

Technical Analysis SentimentNegative
Last Price1.51

Price Trends

50DMA2.52Negative
100DMA4.62Negative
200DMA7.00Negative

Market Momentum

MACD-0.30Positive
RSI33.10Neutral
STOCH33.17Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MTNB, the sentiment is Negative. The current price of 1.51 is below the 20-day moving average (MA) of 2.20, below the 50-day MA of 2.52, and below the 200-day MA of 7.00, indicating a bearish trend. The MACD of -0.30 indicates Positive momentum. The RSI at 33.10 is Neutral, neither overbought nor oversold. The STOCH value of 33.17 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for MTNB.

Matinas BioPharma Risk Analysis

Matinas BioPharma disclosed 59 risk factors in its most recent earnings report. Matinas BioPharma reported the most risks in the "Finance & Corporate" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy

Latest Risks Added

3 New Risks
1.The announcement and pendency of the proposed Business Combination and Stock Sale may adversely affect our business, financial condition and results of operations.Q2, 2026
2.Our stockholders will have a reduced ownership and voting interest following the Business Combination and will exercise less influence over management.Q2, 2026
3.Failure to consummate the Business Combination and Stock Sale within the expected timeframe or at all could have a material adverse impact on our business, financial condition and results of operations and could result in a winddown, dissolution or other liquidation process.Q2, 2026

Matinas BioPharma Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

MTNB against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
APREAPRE44Neutral$6.10M-0.45-46.72%―-99.38%53.42%
HCWBHCWB42Neutral$2.46M-0.02-142.16%―707.02%70.52%
NCNANCNA42Neutral$4.35M-0.25-41.95%――99.50%
ADILADIL40Underperform$10.00M-0.30-1693.21%――45.78%
MTNBMTNB37Underperform$1.48M-0.08-181.45%――68.91%

* Healthcare Sector Average

Performance Comparison

-75%-50%-25%0%25%MTNBNCNAADILSILOAPREHCWBDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
MTNB and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
MTNBMatinas BioPharma Holdings1.51-18.59-92.49%
NCNANucana Plc1.01-2.93-74.37%
ADILAdial Pharma3.81-4.81-55.83%
SILOSilo Pharma Inc1.23-6.57-84.23%
APREAprea Therapeutics, Inc.0.48-0.92-65.43%
HCWBHcw Biologics, Inc.1.10-20.50-94.91%

Matinas BioPharma Corporate Events

Delistings and Listing ChangesRegulatory Filings and ComplianceStock Split

Matinas BioPharma Implements One-for-Fifteen Reverse Stock Split

Neutral
Sep 28, 2026

On September 25, 2026, Matinas BioPharma filed a Certificate of Amendment in Delaware to implement a one-for-fifteen reverse stock split of its common stock, which became effective at 12:01 a.m. Eastern Time on September 28, 2026. Subject to NYSE Ame...

Business Operations and StrategyDelistings and Listing ChangesRegulatory Filings and ComplianceStock Split

Matinas BioPharma Announces One-for-Fifteen Reverse Stock Split

Neutral
Sep 16, 2026

On September 16, 2026, Matinas BioPharma announced that its Board had approved a one-for-fifteen reverse stock split of its common stock, following stockholder authorization granted at the June 23, 2025 annual meeting. The reverse split will take eff...

Delistings and Listing ChangesRegulatory Filings and Compliance

Matinas BioPharma Faces NYSE American Compliance Challenges

Negative
Sep 4, 2026

On August 31, 2026, Matinas BioPharma received a notice from NYSE American that it is not in compliance with the exchange’s continued listing standards, citing stockholders’ equity of $1.8 million as of June 30, 2026 and losses in its fiv...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Oct 20, 2026