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Noile-Immune Biotech Inc. (4893) AI Stock Analysis

JP:4893

Noile-Immune Biotech Inc.

(TSE/TYO:4893)

Select Model
Rating:37Underperform
Price Target:JPY 79.00▼(-3.66% Downside)
Action:downgraded
Date:10/08/26

The overall score is at the minimum of 37, reflecting a convergence of significant risks. The company is a pre-revenue biotech with deep operating losses and negative cash flows, though its debt-free balance sheet provides a temporary buffer. Technicals are extremely weak, with the stock in a deep downtrend and oversold conditions. The negative P/E and lack of dividend further underscore the lack of current profitability. The primary risk is continued cash burn without commercial traction.

Positive Factors
Debt-free balance sheetThe absence of debt lowers leverage and interest-burden risk, giving the company more financial flexibility than a similarly unprofitable business with borrowings. Its sizeable equity base provides some cushion for continued development, although ongoing losses can gradually erode that protection.
Negative Factors
Sharp revenue contractionSevere and repeated revenue contraction weakens the foundation for commercialization and makes future operating leverage harder to achieve. Declining sales also reduce the company’s ability to absorb fixed research and corporate costs, increasing dependence on its existing equity resources.

Noile-Immune Biotech Inc. (4893) vs. iShares MSCI Japan ETF (EWJ)

-60%-40%-20%0%20%40%JP:4893-46.41%EWJ+16.91%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
JPY 3.56B
Dividend Yield
―
Average Volume (3M)
193.04K
Price to Earnings (P/E)
-4.7
Beta (1Y)
0.80
Revenue Growth
-92.30%
EPS Growth
-8.80%
Country
Japan
Employees
23
Sector
General
Sector Strength
55
Industry
Biotechnology

Noile-Immune Biotech Inc. Business Overview & Revenue Model

Company Description

Established in 2015 and based in Minato, Japan, this company is dedicated to exploring and advancing CAR-T cell technology for use in cancer immunotherapy treatments.

Noile-Immune Biotech Inc. Financial Statement Overview

Summary

Financial performance is weak. The Income Statement Score (10) reflects volatile, declining revenue and deep operating losses. The Cash Flow Score (20) shows persistent negative operating cash flow. These are partially offset by a strong Balance Sheet Score (65) with no debt and a solid equity base. Overall, the company is burning cash with minimal revenue, a high-risk profile typical of early-stage biotech.

Income Statement

10Very Negative

Balance Sheet

65Positive

Cash Flow

20Very Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue715.00K5.00M7.59M316.82M625.78M100.73M
Gross Profit05.00M7.39M314.56M618.71M77.83M
EBITDA-800.73M-797.25M-1.07B-775.39M-106.34M-767.51M
Net Income-753.88M-793.54M-964.46M-1.13B-386.62M-795.03M
Balance Sheet
Total Assets3.66B4.01B4.80B5.78B4.64B4.27B
Cash, Cash Equivalents and Short-Term Investments3.54B3.92B4.67B5.56B4.52B4.14B
Total Debt000000
Total Liabilities90.34M79.64M74.67M91.49M340.42M85.72M
Stockholders Equity3.57B3.93B4.73B5.69B4.30B4.19B
Cash Flow
Free Cash Flow00-887.81M-873.08M-107.18M-777.14M
Operating Cash Flow0-752.22M-887.81M-873.08M-107.18M-777.14M
Investing Cash Flow0-378.00K557.00K-5.32M0-4.03M
Financing Cash Flow0-20.00K2.50M1.91B487.62M2.37B

Noile-Immune Biotech Inc. Technical Analysis

Technical Analysis SentimentNegative
Last Price82.00

Price Trends

50DMA120.58Negative
100DMA125.68Negative
200DMA137.66Negative

Market Momentum

MACD-10.25Negative
RSI15.32Positive
STOCH18.28Positive

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4893, the sentiment is Negative. The current price of 82.00 is below the 20-day moving average (MA) of 94.40, below the 50-day MA of 120.58, and below the 200-day MA of 137.66, indicating a bearish trend. The MACD of -10.25 indicates Negative momentum. The RSI at 15.32 is Positive, neither overbought nor oversold. The STOCH value of 18.28 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4893.

Noile-Immune Biotech Inc. Peers Comparison

Overall Rating

UnderperformOutperform
Sector (55)

Financial Indicators

JP:4893 against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
Sector *55Neutral$6.65B3.83-15.92%6.20%10.91%7.18%
JP:3750JP:375045NeutralJPY 7.14B-12.36――15.47%69.34%
JP:4880JP:488045NeutralJPY 5.68B56.94―1.75%-9.94%―
JP:4564JP:456442NeutralJPY 7.35B-7.20-42.79%―-8.58%19.03%
JP:4599JP:459942NeutralJPY 8.71B-4.51―――4.85%
JP:4893JP:489337UnderperformJPY 3.69B-4.71――-92.30%-8.80%
JP:7776JP:777637UnderperformJPY 7.43B-6.32――-56.16%3.12%

* General Sector Average

Performance Comparison

-40%-20%0%20%JP:4893JP:4564JP:3750JP:4599JP:4880JP:7776Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
JP:4893 and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
JP:4893Noile-Immune Biotech Inc.82.00-70.00-46.05%
JP:4564OncoTherapy Science, Inc.17.00-7.00-29.17%
JP:3750Cytori Cell Research Institute, Inc.776.00-64.00-7.62%
JP:4599StemRIM Inc.134.00-139.00-50.92%
JP:4880CellSource Co., Ltd.283.00-228.00-44.62%
JP:7776CellSeed Inc.183.00-254.00-58.12%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Oct 08, 2026