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Ribomic, Inc. (JP:4591)
:4591
Japanese Market
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Ribomic, Inc. (4591) AI Stock Analysis

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JP:4591

Ribomic, Inc.

(4591)

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Neutral 49 (OpenAI - Gpt-5.6Sol)
Rating:49Neutral
Price Target:
¥85.00
▲(13.33% Upside)
Action:Reiterated
Date:07/09/26
The score is primarily held back by weak financial performance—deep ongoing losses and continued cash burn—despite the benefit of a debt-free balance sheet. Technicals are supportive in the near term (positive MACD; price above key short-term averages), but overbought readings raise pullback risk. Valuation is constrained by unprofitability (negative P/E) and no provided dividend yield.
Positive Factors
Debt-free, net-cash balance sheet
Zero debt and a net-cash position reduce insolvency and refinancing pressure, giving Ribomic more flexibility to fund research while preserving optionality through a difficult development period. The meaningful equity base also provides a stronger cushion than leveraged biotech peers.
Negative Factors
Persistent deep losses
Persistent operating and net losses show that the current business remains far from self-sustaining, despite the latest revenue rebound. Extremely negative margins indicate that sales are still too small relative to expenses, making profitability dependent on substantial future improvement.
Read all positive and negative factors
Positive Factors
Negative Factors
Debt-free, net-cash balance sheet
Zero debt and a net-cash position reduce insolvency and refinancing pressure, giving Ribomic more flexibility to fund research while preserving optionality through a difficult development period. The meaningful equity base also provides a stronger cushion than leveraged biotech peers.
Read all positive factors

Ribomic, Inc. (4591) vs. iShares MSCI Japan ETF (EWJ)

Ribomic, Inc. Business Overview & Revenue Model

Company Description
Ribomic Inc. is a Japanese biopharmaceutical company dedicated to identifying and advancing medicinal compounds. The firm employs RNA aptamers in its drug development efforts, targeting various significant health issues such as wet age-related mac...

Ribomic, Inc. Financial Statement Overview

Summary
Financials reflect an early-stage biotech profile: the income statement and cash flow are very weak due to persistent, large losses and ongoing negative operating/free cash flow (cash burn). The key offsetting strength is a debt-free, net-cash balance sheet, but equity has been trending down as losses continue.
Income Statement
14
Very Negative
Balance Sheet
62
Positive
Cash Flow
18
Very Negative
BreakdownTTMMar 2026Mar 2025Mar 2024Mar 2023Mar 2022
Income Statement
Total Revenue7.50M3.00M2.11M0.0065.97M80.91M
Gross Profit3.85M-995.00K1.19M-10.50M0.000.00
EBITDA-1.23B-1.20B-1.05B-1.11B-1.79B-1.73B
Net Income-1.19B-1.15B-1.02B-1.02B-1.65B-1.68B
Balance Sheet
Total Assets2.89B2.98B3.19B3.55B4.58B4.95B
Cash, Cash Equivalents and Short-Term Investments2.78B2.83B3.04B3.40B4.33B4.70B
Total Debt0.000.000.000.000.000.00
Total Liabilities150.03M135.09M142.21M155.81M199.30M260.53M
Stockholders Equity2.74B2.84B3.04B3.39B4.38B4.69B
Cash Flow
Free Cash Flow-255.11M-1.12B-1.03B-955.48M-1.73B-1.51B
Operating Cash Flow-250.76M-1.11B-996.97M-932.76M-1.71B-1.50B
Investing Cash Flow-54.35M289.83M67.18M177.27M276.35M689.56M
Financing Cash Flow347.70M911.05M667.26M27.65M1.33B354.72M

Ribomic, Inc. Technical Analysis

Technical Analysis Sentiment
Positive
Last Price75.00
Price Trends
50DMA
76.66
Positive
100DMA
74.72
Positive
200DMA
80.08
Positive
Market Momentum
MACD
3.30
Positive
RSI
54.43
Neutral
STOCH
23.88
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4591, the sentiment is Positive. The current price of 75 is below the 20-day moving average (MA) of 83.55, below the 50-day MA of 76.66, and below the 200-day MA of 80.08, indicating a bullish trend. The MACD of 3.30 indicates Positive momentum. The RSI at 54.43 is Neutral, neither overbought nor oversold. The STOCH value of 23.88 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JP:4591.

Ribomic, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (55)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
55
Neutral
$6.65B3.83-15.92%6.20%10.91%7.18%
50
Neutral
¥4.63B-1.223.92%-21.55%-497.97%
50
Neutral
¥15.18B-11.55-8.52%
49
Neutral
¥4.81B-3.681135.58%2.37%
48
Neutral
¥141.32B-38.88-7.17%0.62%27.66%
44
Neutral
¥9.34B-7.43-33.61%74.24%-7.78%
* General Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4591
Ribomic, Inc.
84.00
-22.00
-20.75%
JP:4587
Peptidream
1,096.00
-623.50
-36.26%
JP:4571
NanoCarrier Co., Ltd.
100.00
-66.00
-39.76%
JP:2183
Linical Co., Ltd.
204.00
-127.75
-38.51%
JP:4575
CanBas Co., Ltd.
767.00
-360.00
-31.94%

Ribomic, Inc. Corporate Events

Ribomic Completes Site Network for Phase 3 Achondroplasia Trial in Japan
Aug 24, 2026
Ribomic has completed the establishment of all planned clinical trial sites for its Phase 3 study of umedaptanib pegol in paediatric achondroplasia patients in Japan, securing Institutional Review Board approval at six additional locations to reac...
Ribomic Posts Quarterly Loss but Maintains Strong Equity Base and Full-Year Outlook
Aug 13, 2026
Ribomic reported non-consolidated results for the quarter ended June 30, 2026, posting modest operating revenue of ¥4 million and a net loss of ¥270 million, slightly narrower in per-share terms than the prior-year period. Total assets d...
RIBOMIC Begins Phase 3 Trial of Orphan Drug Umedaptanib Pegol for Paediatric Achondroplasia
Jul 2, 2026
RIBOMIC, Inc., a Tokyo-listed clinical-stage pharmaceutical company focused on aptamer-based nucleic acid therapeutics, is advancing treatments for rare and intractable conditions. Its lead candidate, umedaptanib pegol (RBM-007), targets fibroblas...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 09, 2026