Drug EfficacyPreclinical data showed that a triple combination of IMM-1-104, gemcitabine, and paclitaxel led to the strongest tumor volume reduction.
Safety ProfileIMM-1-104 showed an excellent safety and tolerability profile with no dose-limiting toxicities or serious treatment-related adverse events, potentially best-in-class.
Treatment PotentialTreatment with '104 suppressed expression of genes associated with chemotherapy resistance, which may enhance the efficacy of chemotherapy.