TipRanks
Go Ultimate55% OFF

ANGLE plc (CLBX) AI Stock Analysis

GB:CLBX

ANGLE plc

(LSE:CLBX)

Select Model
Rating:40Underperform
Price Target:GBX 0.85â–²(52.32% Upside)
Action:reiterated
Date:11/26/25

The stock scores poorly due to critical financial weaknesses including unsustainable losses and cash burn, compounded by a strong technical downtrend. Negative valuation and funding risks from the earnings call further weigh on the outlook, despite progress in strategic partnerships.

Positive Factors
Strategic partnerships enabling commercializationA large medtech collaboration with Myriad Genetics creates durable commercial distribution capabilities and scales go-to-market reach for Parsortix. This structural partnership can accelerate adoption, provide commercialization expertise, and open payer and clinical channels beyond one-off research sales.
Negative Factors
Limited cash runwayA cash runway ending in Q1 2026 creates a structural financing risk that can force dilutive capital raises or constrain strategic investments. Management time and resources may be diverted to fundraising, slowing commercialization and accreditation execution over the next 2–6 months.

ANGLE plc (CLBX) vs. iShares MSCI United Kingdom ETF (EWC)

-80%-60%-40%-20%0%20%40%GB:CLBX-72.73%EWC+24.02%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
GBP 6.82M
Dividend Yield
―
Average Volume (3M)
1.99M
Price to Earnings (P/E)
-0.5
Beta (1Y)
1.09
Revenue Growth
-56.10%
EPS Growth
41.10%
Country
UK
Employees
114
Sector
Healthcare
Sector Strength
51
Industry
Medical - Diagnostics & Research

ANGLE plc Business Overview & Revenue Model

Company Description

CelLBxHealth plc is a medical diagnostics firm specializing in the creation of cancer detection solutions, with operations spanning the United Kingdom, broader Europe, North America, and other global markets. A flagship offering is the Parsortix PC1...

How the Company Makes Money

ANGLE generates revenue primarily through the sale of its Parsortix systems and related consumables. The company also earns income from service contracts and collaborations with research institutions and pharmaceutical companies that utilize its tech...

ANGLE plc Earnings Call Summary

Earnings Call Date:Sep 08, 2025(Q2-2025)|% Change Since:-90.26%|Next Earnings Date:Jul 30, 2019
Earnings Call SentimentNeutral

ANGLE's earnings call presented a balanced outlook with significant achievements in pharma collaborations and technology development, but also faced challenges from adverse market conditions affecting revenue and the need for additional funding.

Positive Updates

Successful Completion of Large Pharma Projects
ANGLE successfully completed three large pharma projects with Eisai and AstraZeneca, demonstrating the utility of the Parsortix system in HER2 breast cancer trials and developing assays for DNA Damage Response and Androgen Receptor.

Negative Updates

Revenue Decline Due to Market Conditions
Pharma revenue was down and product revenue was flat due to market volatility and tariff concerns, resulting in slowed decision-making and a delay in conversion of pipeline opportunities.

Company Guidance

During the ANGLE 2025 Interim Results Call, CEO Andrew Newland provided comprehensive guidance on the company's financial and operational progress for the first half of the fiscal year. Despite facing adverse market conditions that pressured revenue, with pharma revenue down and product revenue flat compared to the prior year, ANGLE has made significant strides in commercialization and development. Key achievements include the completion of three major pharma projects with Eisai and AstraZeneca, the development of the DNA dual analysis using Illumina's NGS assay, and the commencement of a collaboration with Myriad Genetics for large-scale commercialization of the Parsortix system. The company has maintained tight cost control, reducing operating expenditure by 12%, and holds a cash position of GBP 6.6 million, with a runway extending into Q1 2026. Despite the challenging environment, ANGLE anticipates further developments with multiple large pharma and med tech companies and is actively pursuing additional funding sources to ensure continued growth and innovation in its cancer diagnostic solutions.

ANGLE plc Financial Statement Overview

Summary

Severe financial challenges with steep losses (net margin -497%), declining revenue (-4.3% TTM), and negative cash flows. Low debt provides stability, but negative ROE (-104.7%) indicates significant equity erosion.

Income Statement

10Very Negative

Balance Sheet

40Negative

Cash Flow

15Very Negative
Financial statement breakdown
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue2.62M2.86M2.19M1.04M1.01M762.00K
Gross Profit1.63M1.78M-408.00K613.00K711.00K597.00K
EBITDA-15.60M-13.02M-19.48M-22.06M-15.74M-12.29M
Net Income-15.78M-14.22M-20.13M-21.69M-15.01M-11.61M
Balance Sheet
Total Assets18.08M25.46M31.18M49.87M47.31M39.05M
Cash, Cash Equivalents and Short-Term Investments5.27M10.43M16.22M31.90M31.84M28.62M
Total Debt3.67M4.21M4.55M5.00M2.34M1.36M
Total Liabilities6.39M7.02M8.24M9.80M6.99M4.71M
Stockholders Equity11.69M18.44M22.94M40.06M40.33M34.34M
Cash Flow
Free Cash Flow-11.62M-13.89M-15.12M-17.94M-15.80M-8.35M
Operating Cash Flow-11.25M-13.45M-14.46M-16.05M-14.01M-7.85M
Investing Cash Flow-491.50K-48.00K-203.00K-1.75M14.77M-1.97M
Financing Cash Flow-2.05M7.67M-1.13M18.10M18.99M18.14M

ANGLE plc Technical Analysis

Technical Analysis SentimentNegative
Last Price0.56

Price Trends

50DMA0.92Negative
100DMA1.17Negative
200DMA1.15Negative

Market Momentum

MACD-0.10Positive
RSI19.85Positive
STOCH26.98Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:CLBX, the sentiment is Negative. The current price of 0.56 is below the 20-day moving average (MA) of 0.74, below the 50-day MA of 0.92, and below the 200-day MA of 1.15, indicating a bearish trend. The MACD of -0.10 indicates Positive momentum. The RSI at 19.85 is Positive, neither overbought nor oversold. The STOCH value of 26.98 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GB:CLBX.

ANGLE plc Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

GB:CLBX against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
GB:DXRXGB:DXRX59NeutralGBP 172.63M-635.94-0.68%―20.14%82.22%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
GB:GDRGB:GDR49NeutralGBP 15.65M-0.89-1044.57%―65.60%74.84%
GB:ABDXGB:ABDX46NeutralGBP 22.75M-16.36-34.31%―30.42%43.16%
GB:VRCIGB:VRCI44NeutralGBP 15.32M-0.60-127.57%―77.87%84.36%
GB:CLBXGB:CLBX40UnderperformGBP 6.82M-0.49-104.73%―-56.10%41.10%
GB:PRMGB:PRM37UnderperformGBP 5.10M-1.9923.85%―-16.72%36.28%

* Healthcare Sector Average

Performance Comparison

-50%0%50%100%GB:CLBXGB:GDRGB:PRMGB:DXRXGB:VRCIGB:ABDXDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
GB:CLBX and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
GB:CLBXANGLE plc0.60-1.50-71.43%
GB:GDRGenedrive plc0.97-0.04-3.75%
GB:PRMProteome Sciences1.46-0.19-11.55%
GB:DXRXDiaceutics Plc202.5040.0024.62%
GB:VRCIVerici Dx Plc0.23-0.40-63.20%
GB:ABDXAbingdon Health PLC9.002.7544.00%

ANGLE plc Corporate Events

Business Operations and StrategyDelistings and Listing ChangesFinancial Disclosures

CelLBxHealth Tightens Costs and Reshapes Strategy as 2025 Revenues Miss Target

Negative
Jan 16, 2026

CelLBxHealth reported preliminary unaudited 2025 revenues of about £1.4 million, slightly below expectations after roughly £0.2 million of anticipated sales slipped into the first quarter of 2026, while year-end cash stood at £7.3 mill...

Business Operations and StrategyExecutive/Board Changes

CelLBxHealth refreshes board and appoints new CEO to drive CTC growth strategy

Positive
Jan 12, 2026

CelLBxHealth plc has strengthened its board with the immediate appointment of Peter Collins as chief executive officer and Klaas de Boer, Kim Oreskovic and Benjamin Hart as non-executive directors, while non-executive director Joseph Eid will step do...

Business Operations and StrategyPrivate Placements and Financing

CelLBxHealth Executives and ESOT Boost Holdings After Oversubscribed Placing

Positive
Dec 19, 2025

CelLBxHealth plc has disclosed significant share purchases by its top executives following last month’s oversubscribed placing, with Executive Chairman Jan Groen and CEO Peter Collins each acquiring 5 million shares and Finance Director Sin&#23...

Executive/Board ChangesDelistings and Listing ChangesShareholder Meetings

CelLBxHealth Announces Board Changes and Share Capital Reorganization

Positive
Dec 15, 2025

CelLBxHealth plc announced that all resolutions were approved at their General Meeting, paving the way for significant changes, including the transition of Peter Collins from Interim CEO to CEO and the anticipated appointment of new board members in...

Private Placements and Financing

CelLBxHealth Secures Additional Investment from Acacia Funds

Positive
Dec 2, 2025

CelLBxHealth plc announced an additional subscription by Conifer Management, LLC, on behalf of the Acacia funds, for 40,891,541 new ordinary shares, raising approximately £0.4 million. This additional subscription, part of a larger fundraising e...

Business Operations and StrategyPrivate Placements and Financing

CelLBxHealth plc Successfully Closes Retail Offer, Raising £0.96 Million

Positive
Dec 1, 2025

CelLBxHealth plc has successfully closed its Retail Offer, raising approximately £0.96 million, with plans to issue 95,869,449 shares at 1.0 pence each, contingent upon the passing of resolutions at an upcoming General Meeting. The company aims...

Delistings and Listing ChangesPrivate Placements and Financing

CelLBxHealth Announces Update on Fundraising Shares Admission

Positive
Nov 25, 2025

CelLBxHealth plc announced an update regarding the admission of fundraising shares following an oversubscribed placing. The first tranche of 9,090,000 shares is expected to be admitted on December 16, 2025, with a second tranche of up to 770,910,000...

Business Operations and StrategyPrivate Placements and Financing

CelLBxHealth plc Completes Oversubscribed Fundraising to Enhance Market Position

Positive
Nov 25, 2025

CelLBxHealth plc has successfully concluded an oversubscribed placing and subscription, raising approximately £6.8 million through the issuance of new shares at a discounted price. This fundraising effort is aimed at expanding the company’...

Business Operations and StrategyPrivate Placements and FinancingShareholder Meetings

CelLBxHealth Launches Retail Share Offer to Boost Funding

Neutral
Nov 25, 2025

CelLBxHealth plc, a company focusing on healthcare solutions, has announced a retail offer of new ordinary shares at a discounted issue price of 1.0 pence per share. This offer is part of a larger fundraising initiative that includes a conditional pl...

Business Operations and StrategyPrivate Placements and Financing

CelLBxHealth Announces £6.8 Million Fundraising to Drive Commercial Strategy

Positive
Nov 24, 2025

CelLBxHealth plc has announced a proposed fundraising of £6.8 million through a placing, subscription, and retail offer to support its revised business strategy. The company aims to transition from a research-focused organization to a commercial...

Business Operations and StrategyProduct-Related Announcements

CelLBxHealth Partners with QIAGEN to Enhance CTC-Based Research

Positive
Nov 18, 2025

CelLBxHealth plc has announced a collaboration and co-marketing agreement with QIAGEN Manchester Ltd. to advance CTC-based research. This partnership will combine CelLBxHealth’s Parsortix platform with QIAGEN’s molecular technologies to e...

Business Operations and StrategyPrivate Placements and Financing

CelLBxHealth plc Announces £6 Million Fundraising Initiative

Neutral
Nov 5, 2025

CelLBxHealth plc has announced its intention to raise approximately £6 million to extend its cash runway into early 2026. The company is in discussions with shareholders and plans to make an offer to retail investors alongside an institutional p...

Business Operations and StrategyProduct-Related Announcements

CelLBxHealth Unveils Promising Study on CTC Integration with Roche’s Diagnostic Platform

Positive
Nov 5, 2025

CelLBxHealth plc has announced a successful proof-of-concept study demonstrating the compatibility of its Parsortix platform with Roche Tissue Diagnostics’ BenchMark ULTRA automated staining system. This study, presented at the World ADC Confer...

Business Operations and StrategyPrivate Placements and FinancingProduct-Related Announcements

CelLBxHealth’s Parsortix® Platform Recognized as Leading Technology in CTC Analysis

Positive
Nov 4, 2025

CelLBxHealth plc announced a major international expert consensus highlighting the clinical relevance of circulating tumor cell (CTC) analysis in cancer management, with the Parsortix® platform identified as a leading next-generation technology....

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Dec 07, 2025