TipRanks
Go Ultimate55% OFF

Codexis (0I0X) AI Stock Analysis

GB:0I0X

Codexis

(LSE:0I0X)

Rating:―N/A
Action:N/A
Date:―

No summary available

Positive Factors
High and improving product marginsA 73% product gross margin indicates meaningful economic value in Codexis’s enzyme offerings, while the expected high-60% full-year margin supports durability. Margin improvement can strengthen cash conversion and provide operating leverage as commercial volumes expand.
Negative Factors
Sharp revenue contraction and lumpinessA sharp TTM revenue decline, combined with customer-timing variability, weakens visibility into the company’s near-term growth path. Uneven demand can make resource planning difficult and delay the operating scale needed to convert strong margins into sustainable profitability.

Codexis (0I0X) vs. iShares MSCI United Kingdom ETF (EWC)

-60%-40%-20%0%20%40%GB:0I0X-44.88%EWC+21.27%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
Market Cap
$130.31M
Dividend Yield
―
Average Volume (3M)
10.04K
Price to Earnings (P/E)
-3.5
Beta (1Y)
0.49
Revenue Growth
35.89%
EPS Growth
58.70%
Country
UK
Employees
146
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Codexis Business Overview & Revenue Model

Company Description

Codexis, Inc. is a biotechnology firm dedicated to the discovery, development, and commercialization of enzymes and other protein-based solutions. Its diverse portfolio encompasses advanced biocatalyst products and related services, specialized chemi...

Codexis Earnings Call Summary

Earnings Call Date:Aug 10, 2026(Q2-2026)|% Change Since:-26.00%|Next Earnings Date:Nov 11, 2026
Earnings Call SentimentPositive

The call presents a predominantly positive strategic and technical narrative: clear technology milestones (stereochemistry control, Starterless initiation), progressing scale demonstrations (hundreds of grams toward kilogram scale), active CDMO and biopharma engagements, improving product gross margin (73%) and disciplined expense reductions. Financially, the company showed a modest year-over-year revenue decline in the quarter, a pre-financing drop in cash balance, and an ongoing net loss. These negatives are mitigated by a successful $25M financing that restores pro forma cash to ~$79.8M and management's stated cash runway through 2028, plus reiterated 2026 revenue guidance ($70M–$76M). The primary remaining risks are revenue lumpiness, the need to convert pilot/tech-transfer activity into firm commercial contracts, and successfully industrializing ECOsynthesis at commercial scale. On balance, highlights (technical differentiation, commercial engagement, margin improvement, financing and runway) outweigh the lowlights (quarterly revenue decline, cash drawdown prior to financing, execution risk), supporting a constructive view of progress and prospects.

Positive Updates

Revenue and Guidance
Q2 2026 revenue of $14.9M (vs $15.3M in Q2 2025, -2.6%). Company reiterates 2026 revenue guidance of $70M–$76M and expects revenue to be weighted to the second half of 2026.

Negative Updates

Quarterly Revenue Decline
Q2 2026 revenue fell to $14.9M from $15.3M year-over-year (-2.6%), reflecting continued lumpiness and dependence on customer timing.

Company Guidance

Codexis reiterated 2026 revenue guidance of $70–$76 million (expected to be back‑half weighted) after reporting Q2 revenue of $14.9M (vs. $15.3M year‑ago) and a Q2 product gross margin of 73% (management expects full‑year gross margins to improve into the high‑60s); Q2 R&D was $11.7M and SG&A $10.9M, with a net loss of $12.0M (vs. $13.3M). The company ended Q2 with $54.9M in cash and, following a $25M net equity financing, a pro‑forma cash balance of ~ $79.8M that management says funds operations and capex through 2028 (including ~ $25M of planned GMP facility construction); operational milestones include advancing ECOsynthesis to hundreds of grams today, a 500‑gram pilot target in the Eco Innovation Lab, a goal of kilogram‑scale prior to GMP start, completion of small‑scale tech transfers with three CDMOs (one in advanced long‑term commercial negotiations), supporting 14 commercial enzyme‑dependent products (four approvals in 2026 and one label expansion), 15 programs in Phase II/III with seven readouts expected in the next two years, and broader industry context of an expected ~30‑fold increase in siRNA demand by 2035 and an estimated ~70% capital efficiency advantage for ECOsynthesis.

Codexis Risk Analysis

Codexis disclosed 50 risk factors in its most recent earnings report. Codexis reported the most risks in the "Finance & Corporate" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy

Latest Risks Added

2 New Risks
1.Our business may be affected by the evolving regulatory framework for AI TechnologiesQ4, 2025
2.International trade policies, including tariffs, sanctions and trade barriers, may adversely affect our business.Q4, 2025

Codexis Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

GB:0I0X against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
CGENCGEN65Neutral$187.56M5.2742.57%―234.18%―
MXCTMXCT56Neutral$164.10M-4.76-21.01%―-13.15%21.12%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
CBUSCBUS50Neutral$98.59M-0.78-320.60%―-10.30%84.17%
DTILDTIL43Neutral$194.87M-2.53-91.60%―3472.96%67.74%
ADAGADAG41Neutral$168.53M-5.32-29.09%―8906.15%41.48%

* Healthcare Sector Average

Performance Comparison

-50%0%50%100%150%GB:0I0XCGENMXCTCBUSDTILADAGDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
GB:0I0X and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
GB:0I0XCodexis1.19-1.04-46.64%
CGENCompugen1.980.2514.45%
MXCTMaxCyte, Inc.1.59-0.02-1.24%
CBUSCibus, Inc.1.29-0.15-10.42%
DTILPrecision Biosciences7.06-0.30-4.08%
ADAGAdagene, Inc.2.510.7240.22%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.