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Poxel SA (POXEL) Price & Analysis
POXEL Stock Chart & Stats
- Day’s Range
- EUR 0.16 - EUR 0.17
- 52-Week Range
- EUR 0.13 - EUR 0.48
- Previous Close
- EUR 0.17
- Volume
- 292.16K
- Average Volume (3M)
- 999.56K
- Market Cap
- EUR 8.87M
- Enterprise Value
- EUR 85.28M
- Total Cash (Recent Filing)
- EUR 2.06M
- Total Debt (Recent Filing)
- EUR 60.99M
- Price to Earnings (P/E)
- ―
- Beta
- 0.08
- Next Earnings
- Mar 24, 2027
- EPS Estimate
- N/A
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Commercial Partnership With Sumitomo Pharma
A revenue-generating, arm’s-length commercialization partnership in Japan provides durable non-dilutive cash via milestones/royalties and shifts commercialization burden to an established local partner. This reduces short-term capex needs and supports predictable collaboration receipts over coming quarters.
Sharp Revenue Rebound In 2024
A material revenue inflection indicates commercial traction for marketed products or recognition of partnership receipts. Sustained top-line recovery over multiple quarters would improve operating leverage potential and validate the commercial model versus purely pre-revenue peers.
Focused Metabolic/NASH Clinical Pipeline
A coherent R&D focus on diabetes and NASH leverages prior regulatory/commercial experience with imeglimin and targets large, structural markets. Small‑molecule assets can be more cost-efficient to develop and attract partnering/licensing opportunities, supporting multiple long-term value pathways.
Bears Say
Highly Stressed Balance Sheet
Deep negative equity combined with rising debt materially limits financial flexibility, increasing refinancing and dilution risk. Over a multi‑month horizon this constrains runway for R&D and commercialization investments and raises the probability management must seek costly external funding.
Persistent Negative Operating Cash Flow
Sustained negative operating cash flow means the company cannot self-fund growth and depends on partners, milestone receipts, or financing. That reliance impairs long‑term planning, elevates dilution risk, and could limit ability to scale commercialization or fund pivotal trials without external capital.
Ongoing Unprofitability And Volatile Margins
Despite revenue gains, persistent negative profitability and historical margin swings indicate weak operating leverage and unstable unit economics. Over the medium term, sustainable value creation depends on consistent margin recovery and cost control, which are not yet demonstrated.
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Company Description
Poxel SA
Poxel S.A. is a clinical-stage biopharmaceutical firm dedicated to discovering innovative therapies for a range of conditions, including metabolic disorders, type 2 diabetes, and liver ailments. Its most advanced investigational drug, Imeglimin, is an oral medication candidate for type 2 diabetes. This treatment has successfully completed Phase III trials in Japan and is currently undergoing Phase III development in both the United States and Europe. Imeglimin works by enhancing pancreatic beta cell function, reducing insulin resistance, and mitigating significant cardiovascular and metabolic risk factors like elevated blood lipid levels and excessive body weight. Beyond Imeglimin, Poxel is also advancing PXL770, an activator of the adenosine monophosphate-activated protein kinase (AMPK) enzyme. This compound is presently in a Phase 2a clinical trial, targeting various chronic metabolic diseases, notably those affecting the liver, such as non-alcoholic steatohepatitis (NASH). Furthermore, the company has strategic collaborations for other pipeline assets. Under a licensing agreement with Enyo Pharma S.A.S., Poxel is developing PXL007 (also known as EYP001), a synthetic non-steroidal and non-bile acid FXR agonist, which is currently in a Phase II study for treating hepatitis B and NASH. Another partnership with DeuteRx LLC focuses on PXL065, a mitochondrial pyruvate carrier inhibitor, now in a Phase I clinical trial specifically for NASH. Established in 2009, Poxel S.A. operates from its headquarters in Lyon, France.
- Sector
- General
- Industry
- Biotechnology
- CEO
- Yves Decadt
- Employees
- 5
- Website
- www.poxelpharma.com
- Address
- Immeuble Le Sunway, Lyon, ARA, 69007, FR
Poxel SA (POXEL) Earnings & Revenues
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 5 | 5 | 12 |
| Technical Analysis | 3 | 5 | 2 |
| Moving Averages | 2 | 0 | 10 |




