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Innate Pharma SA (IPH) AI Stock Analysis

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FR:IPH

Innate Pharma SA

(Paris:IPH)

Select Model
Rating:43Neutral
Price Target:EUR 1.00â–¼(-16.25% Downside)
Action:reiterated
Date:09/22/26

The overall score is driven primarily by very weak financial health, including collapsing revenue, sustained losses, negative equity, and continued cash burn, which indicate high risk despite some operational stability. Technical indicators currently show soft momentum with the stock trading below most key moving averages, offering only limited support to the profile. Valuation is constrained by loss-making operations and lack of dividends, while a positive, catalyst-rich earnings call with extended cash runway and strong partnerships provides a meaningful but insufficient offset to the underlying financial distress.

Positive Factors
Lacutamab partnership and Phase 3 progressThe Sobi collaboration provides external development support for lacutamab while Phase 3 execution and FDA clearance advance the asset toward potential registration. This reduces standalone development burden and creates a clearer pathway to future commercial participation.
Negative Factors
Sharp revenue and profitability deteriorationThe steep 2025 revenue decline and widening operating losses show that current earnings capacity remains weak and dependent on variable partner income or development activity. Persistently negative profitability limits internal reinvestment and increases reliance on external capital.

Innate Pharma SA (IPH) vs. iShares MSCI France ETF (EWQ)

-40%-20%0%20%40%60%FR:IPH-20.72%EWQ-0.23%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
EUR 141.70M
Dividend Yield
―
Average Volume (3M)
459.00K
Price to Earnings (P/E)
-2.3
Beta (1Y)
0.83
Revenue Growth
-29.48%
EPS Growth
7.91%
Country
France
Employees
120
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Innate Pharma SA Business Overview & Revenue Model

Company Description

Innate Pharma S.A. is a biotechnology firm dedicated to the discovery, development, and commercialization of innovative antibody-based therapies, primarily for cancer indications, operating both in France and internationally. The company's pipeline i...

Innate Pharma SA Earnings Call Summary

Earnings Call Date:Sep 16, 2026(Q2-2026)|% Change Since:-23.46%|Next Earnings Date:Mar 24, 2027
Earnings Call SentimentPositive

The call was broadly positive, with significant progress across the portfolio, including the closing of the Sobi partnership, initiation of lacutamab's Phase 3 study, completion of IPH4.5 thousand dose escalation, completion of PACIFIC-9 enrollment, positive preliminary IPH4.5 thousand activity and safety observations, and a projected cash runway through the end of the first quarter of 2028. The main constraints were that IPH4.5 thousand data remain early, enrollment in its non-small cell lung cancer cohort was somewhat lower, and broader development could require additional funding.

Positive Updates

Lacutamab Partnership Closed and Phase 3 Initiated
The strategic partnership with Sobi to advance lacutamab in T-cell lymphoma became effective following deal closing. Innate initiated the TELLOMAK-3 Phase 3 study, with the first patient expected in the first quarter of 2027.

Negative Updates

Early-Stage Nature of IPH4.5 thousand Data
Management emphasized that the objective responses and other activity observed for IPH4.5 thousand in heavily pretreated post-enfortumab vedotin urothelial cancer patients remain early Phase 1 observations. The upcoming dataset is intended to help determine how best to advance the program.

Company Guidance

Innate is targeting the first patient in TELLOMAK-3 in Q1 2027, with a filing for accelerated approval in Sezary Syndrome currently planned for the second half of 2027; the company expects lacutamab to be listed in the NCCN guidelines for both Sezary Syndrome and mycosis fungoides and expects some off label usage in the first line setting. PACIFIC-9 enrollment is complete, with the Phase 3 readout expected in the second half of 2026, and IPH4.5 thousand initial Phase 1 dose escalation data are scheduled for November 18, 2026; the company expects relevant and informative safety data and response data from 11 different indications and 76 patients. The $75 million Sobi upfront payment and €30 million equity offering, representing €28 million in expected net proceeds, are expected to extend cash runway through the end of the first quarter of 2028, and the company is funded to take IPH4.5 thousand forward seamlessly into dose optimization, while broadening the program across additional tumor types would require additional funding. Pricing research established that lacutamab can be priced between $500 thousand and $650 thousand per patient per annum, and the monalizumab agreement includes up to $825 million in additional potential milestones, double digit royalties outside Europe, and 50% profit sharing in Europe.

Innate Pharma SA Financial Statement Overview

Summary

Score reflects collapsing revenue from €70M in 2020 to €2.8M in 2025, persistent deep losses, negative equity and shrinking assets, and ongoing cash burn with only modest improvement in operating cash flow.

Income Statement

25Negative

Balance Sheet

35Negative

Cash Flow

30Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue1.04M2.79M12.62M51.90M49.64M12.11M
Gross Profit18.45M2.79M-31.86M5.62M6.01M-34.89M
EBITDA-52.20M-55.97M-50.99M-1.84M-61.30M-43.23M
Net Income-47.46M-49.18M-49.47M-7.57M-58.10M-52.81M
Balance Sheet
Total Assets34.73M62.72M111.06M184.19M207.86M267.50M
Cash, Cash Equivalents and Short-Term Investments10.90M34.31M80.77M92.46M101.48M119.84M
Total Debt20.21M22.57M31.37M39.89M42.25M44.25M
Total Liabilities75.23M84.42M102.22M132.29M153.71M160.06M
Stockholders Equity-40.51M-21.70M8.83M51.90M54.15M107.44M
Cash Flow
Free Cash Flow-42.81M-52.90M-7.29M-34.91M-20.28M-59.79M
Operating Cash Flow-42.63M-52.76M-6.90M-32.56M-19.15M-58.46M
Investing Cash Flow2.34M7.29M9.20M20.63M1.88M-917.00K
Financing Cash Flow-6.77M6.07M-6.01M-1.97M-1.83M26.82M

Innate Pharma SA Technical Analysis

Technical Analysis SentimentNegative
Last Price1.19

Price Trends

50DMA1.47Negative
100DMA1.56Negative
200DMA1.48Negative

Market Momentum

MACD-0.06Negative
RSI30.16Neutral
STOCH22.75Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For FR:IPH, the sentiment is Negative. The current price of 1.19 is below the 20-day moving average (MA) of 1.28, below the 50-day MA of 1.47, and below the 200-day MA of 1.48, indicating a bearish trend. The MACD of -0.06 indicates Negative momentum. The RSI at 30.16 is Neutral, neither overbought nor oversold. The STOCH value of 22.75 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for FR:IPH.

Innate Pharma SA Risk Analysis

Innate Pharma SA disclosed 89 risk factors in its most recent earnings report. Innate Pharma SA reported the most risks in the "Tech & Innovation" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Tech & Innovation - Risks related to the company’s reliance on technology and ability to make innovative products

Latest Risks Added

1 New Risk
1.The Company relies on certain independent organizations, partners, advisors and consultants to provide certain services and needs to hire new employees and expand its use of service providers.Q4, 2023

Innate Pharma SA Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

FR:IPH against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
FR:NANOFR:NANO46NeutralEUR 1.29B-23.2289.71%―――
FR:TNGFR:TNG46NeutralEUR 208.15M-4.66-29.36%―189.81%38.50%
FR:ABVXFR:ABVX44NeutralEUR 6.66B-16.82-85.88%―――
FR:IPHFR:IPH43NeutralEUR 136.27M-2.34152.56%―-29.48%7.91%
FR:OSEFR:OSE43NeutralEUR 43.53M-1.08-96.73%―-96.25%-197.89%
FR:ALCLSFR:ALCLS39UnderperformEUR 70.88M-1.79-94.14%―-5.98%-8.67%

* Healthcare Sector Average

Performance Comparison

-50%0%50%100%150%FR:IPHFR:ABVXFR:NANOFR:TNGFR:OSEFR:ALCLSDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
FR:IPH and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
FR:IPHInnate Pharma S.A.1.19-0.37-23.85%
FR:ABVXAbivax SA79.25-5.85-6.87%
FR:NANONanobiotix SA25.548.0646.11%
FR:TNGTransgene SA0.78-0.55-41.50%
FR:OSEOSE Immunotherapeutics1.83-3.63-66.45%
FR:ALCLSCellectis SA1.04-1.87-64.23%

Innate Pharma SA Corporate Events

AstraZeneca Pushes Back PACIFIC-9 Lung Cancer Trial Readout, Extending Timeline for Innate Pharma’s Monalizumab

Oct 27, 2026

AstraZeneca has revised the expected timeline for high-level data from the PACIFIC-9 Phase 3 trial, which tests durvalumab in combination with Innate Pharma’s partnered antibody monalizumab or AstraZeneca’s oleclumab in unresectable Stage...

Innate Pharma to Highlight Cancer Immunotherapy Pipeline at November Investor Conferences

Oct 21, 2026

Innate Pharma SA said members of its executive team will participate in two upcoming healthcare investor conferences in November 2026 in New York and London. The company will host a fireside chat at the Stifel Healthcare Conference, with the presenta...

Innate Pharma to Host Q3 2026 Business Update Call

Oct 20, 2026

Innate Pharma SA, a Marseille-based clinical-stage biotech specializing in cancer immunotherapies, is advancing a pipeline centered on antibody-drug conjugates such as lead candidate IPH4502 for solid tumors, alongside partnered late-stage drugs lacu...

Innate Pharma Secures Sobi Partnership Cash and Extends Runway as Key Oncology Trials Advance

Sep 17, 2026

Innate Pharma has made its strategic partnership with Sobi for lacutamab effective, unlocking an initial $75 million payment and enabling the launch of the Phase 3 TELLOMAK‑3 trial in cutaneous T‑cell lymphoma, with first patient enrollme...

Innate Pharma-Sobi Partnership Closes, Unlocks $75 Million and Phase 3 Lacutamab Trial

Sep 16, 2026

Innate Pharma has confirmed that its previously announced strategic partnership with Sobi has become effective, following the expiration of antitrust waiting periods and fulfillment of closing conditions. The transaction’s completion triggers a...

Innate Pharma to deliver H1 2026 business update via investor webcast

Sep 10, 2026

Innate Pharma SA said it will host a conference call and webcast on September 17, 2026, to present a business update for the first half of 2026 to investors and other stakeholders. The event will feature senior executives including the chief executiv...

Innate Pharma to Highlight Oncology Pipeline at H.C. Wainwright Investment Conference

Sep 2, 2026

Innate Pharma SA said members of its management team will participate in a fireside chat and one‑on‑one meetings at the H.C. Wainwright 28th Annual Global Investment Conference in New York from September 14 to 16, 2026. The discussion, sc...

Innate Pharma to Spotlight Oncology Pipeline at H.C. Wainwright Investor Conference

Sep 2, 2026

Innate Pharma SA said members of its executive team will join a fireside chat and hold one-on-one investor meetings at the H.C. Wainwright 28th Annual Global Investment Conference in New York from September 14 to 16, 2026. The company will webcast th...

Innate Pharma Schedules Investor Call as Oncology Pipeline Advances

Aug 14, 2026

Innate Pharma SA will hold a conference call on August 14, 2026, led by senior management including the CEO, COO, CFO and head of investor relations, with live access and replay available through its website and dedicated online links. The event unde...

Innate Pharma Raises €30 Million in Share Offering to Extend Cash Runway

Aug 14, 2026

Innate Pharma SA has priced a private placement of 17,647,059 new ordinary shares at €1.70 per share, raising gross proceeds of about €30 million, or €27.6 million net, through an offering to qualified and institutional investors in...

Innate Pharma launches €22.5m share placement to fund ADC pipeline and extend runway

Aug 13, 2026

Innate Pharma has launched a roughly €22.5 million private placement of new ordinary shares in Europe, the U.S. and other markets to qualified and institutional investors, with Stifel as sole global coordinator and BTIG as joint bookrunner. The...

Innate Pharma Secures Funding and Advances Lacutamab to Phase 3 With New CMO

Aug 10, 2026

Innate Pharma plans to advance its first-in-class antibody lacutamab into the TELLOMAK-3 Phase 3 confirmatory trial in cutaneous T-cell lymphoma, following its strategic partnership with Sobi. The study is intended to underpin an accelerated approval...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Sep 21, 2026