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Collegium Pharmaceutical (354) AI Stock Analysis

DE:354

Collegium Pharmaceutical

(Frankfurt:354)

Rating:―N/A
Action:N/A
Date:―

No summary available

Positive Factors
ADHD Portfolio GrowthRapid Jornay PM growth and expanding branded market share indicate durable commercial traction in ADHD treatment. Rising prescriptions, prescriber reach, and share support a growing franchise that can diversify Collegium beyond its pressured opioid portfolio over the next several quarters.
Negative Factors
Elevated LeverageDebt remains large relative to equity, leaving Collegium more sensitive to earnings volatility and refinancing conditions. Although leverage improved from prior years, the balance sheet still limits financial flexibility after the Azstarys acquisition and could constrain future capital allocation if performance weakens.

Collegium Pharmaceutical (354) vs. iShares MSCI Germany ETF (EWG)

-40%-20%0%20%40%DE:354-31.82%EWG+4.43%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
Market Cap
EUR 774.82M
Dividend Yield
―
Average Volume (3M)
70
Price to Earnings (P/E)
15.6
Beta (1Y)
0.75
Revenue Growth
6.56%
EPS Growth
25.86%
Country
Germany
Employees
423
Sector
Healthcare
Sector Strength
51
Industry
Drug Manufacturers - Specialty & Generic

Collegium Pharmaceutical Business Overview & Revenue Model

Company Description

Collegium Pharmaceutical, Inc. (COLL) is a specialized pharmaceutical firm dedicated to the development and marketing of medications for pain management. Its diverse product lineup features significant therapies aimed at addressing various pain condi...

Collegium Pharmaceutical Earnings Call Summary

Earnings Call Date:Aug 05, 2026(Q2-2026)|% Change Since:-31.37%|Next Earnings Date:Nov 04, 2026
Earnings Call SentimentPositive

The call highlighted strong, accelerating growth in the ADHD franchise—Jornay PM momentum, the strategic Azstarys acquisition with early revenue and raised guidance, Belbuca growth and incremental formulary wins, and an 8% increase in adjusted EBITDA. Offsetting these positives were meaningful declines in the NUCYNTA franchise driven by authorized generic pricing, a decline in Xtampza ER, a GAAP net loss driven by acquisition-related costs, substantial cash deployed to acquire Azstarys and a modest leverage increase, and potential LOE risk for Belbuca. Overall, management presented a constructive outlook focused on ADHD-led growth and disciplined capital deployment while acknowledging near-term pain portfolio pressures and one-time acquisition impacts.

Positive Updates

Jornay PM Prescription and Revenue Growth
Jornay PM prescriptions grew 13.1% year-over-year; net revenue for Jornay PM was $46.1 million in Q2, up 41% year-over-year. Prescribers exceeded 30,000 (up 17.6% YoY).

Negative Updates

NUCYNTA Franchise Revenue Decline and Authorized Generic Pricing Impact
Total NUCYNTA franchise net revenue declined 24% YoY to $35.2 million in Q2. Revenue was lower-than-expected due to net pricing pressure from authorized generic (AG) agreements; CFO noted AG net realizations ~10%–15% of branded net price for IR and ~20%–25% for ER on AG volume.

Company Guidance

Collegium reaffirmed full‑year guidance for Jornay PM of $190–200 million and raised its Azstarys outlook to $65–75 million, driving updated total product revenue guidance of $825–855 million (about +8% year‑over‑year at the midpoint); adjusted EBITDA was guided to $445–470 million (essentially flat vs. 2025) and Jornay PM gross‑to‑net is expected to remain in the mid‑60% range. Management said the guidance update primarily reflects lower‑than‑expected NUCYNTA revenue due to authorized generic pricing, noted Azstarys generated $12.9 million of initial sales in Q2, and reported Q2 operating cash flow of $71.3 million, ending cash and marketable securities of $129.5 million after using approximately $356 million to fund the Azstarys acquisition, with net debt to adjusted EBITDA of ~2.1x.

Collegium Pharmaceutical Risk Analysis

Collegium Pharmaceutical disclosed 43 risk factors in its most recent earnings report. Collegium Pharmaceutical reported the most risks in the "Legal & Regulatory" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Legal & Regulatory - Litigation, compliance, new legislation, and taxation risks

Latest Risks Added

1 New Risk
1.Our ability to realize the benefits from the Azstarys Acquisition is substantially dependent on the timely and effective integration of the Azstarys operations into our ongoing operations.Q2, 2026

Collegium Pharmaceutical Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

DE:354 against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
ANIPANIP75Outperform$1.65B14.9119.19%―30.90%―
PCRXPCRX62Neutral$1.45B103.352.13%―5.71%―
INDVINDV60Neutral$4.17B9.66-352.94%―16.44%265.06%
AMRXAMRX59Neutral$7.49B43.24-326.75%―9.28%4917.17%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
AQSTAQST49Neutral$488.24M-5.98243.68%―22.56%5.86%

* Healthcare Sector Average

Performance Comparison

-50%0%50%DE:354PCRXANIPINDVAMRXAQSTDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
DE:354 and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
DE:354Collegium Pharmaceutical Inc.21.00-9.80-31.82%
PCRXPacira36.3914.2063.99%
ANIPAni Pharmaceuticals72.00-22.06-23.45%
INDVIndivior PLC35.374.1713.37%
AMRXAmneal Pharma21.5110.3292.14%
AQSTAquestive Therapeutics, Inc.3.89-2.60-40.06%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.