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Connect Biopharma Holdings (CNTB)
NASDAQ:CNTB
US Market
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Connect Biopharma Holdings (CNTB) AI Stock Analysis

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CNTB

Connect Biopharma Holdings

(NASDAQ:CNTB)

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Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$2.00
▼(-18.37% Downside)
Action:Reiterated
Date:06/30/26
The score is held down primarily by weak financial performance (zero 2025 revenue, sizable net losses, and heavy cash burn) and limited valuation support given ongoing losses. Offsetting factors include supportive corporate events (positive trial progress and financing to extend runway) and mostly neutral technical indicators with only modest short-term improvement.
Positive Factors
Clinical Development Progress
Completing enrollment in two Phase 2 studies advances rademikibart toward a meaningful clinical readout. Positive controlled data could support discussions with the FDA and establish a path toward Phase 3 development.
Negative Factors
Lack of Durable Product Revenue
The absence of approved products leaves Connect Biopharma without a dependable operating revenue base. Until a candidate reaches commercialization or a partnership generates recurring economics, financial performance will remain highly dependent on external funding.
Read all positive and negative factors
Positive Factors
Negative Factors
Clinical Development Progress
Completing enrollment in two Phase 2 studies advances rademikibart toward a meaningful clinical readout. Positive controlled data could support discussions with the FDA and establish a path toward Phase 3 development.
Read all positive factors

Connect Biopharma Holdings (CNTB) vs. SPDR S&P 500 ETF (SPY)

Connect Biopharma Holdings Business Overview & Revenue Model

Company Description
Connect Biopharma Holdings Limited is a clinical-stage biopharmaceutical company dedicated to discovering and advancing immune modulators. Its primary objective is to develop treatments for serious autoimmune diseases and various inflammatory cond...
How the Company Makes Money
Connect Biopharma has historically generated little to no recurring revenue from product sales because it is a clinical-stage company without marketed, approved therapies. Its reported revenue, when present, has primarily come from collaboration-r...

Connect Biopharma Holdings Financial Statement Overview

Summary
Overall financial quality is weak: revenue dropped to $0 in 2025 after $26.0M in 2024, net losses remain large (~$55.5M in 2025), and operating/free cash flow are deeply negative (OCF ~-$51.2M and FCF ~-$51.6M in 2025). The balance sheet helps (very low debt), but equity and assets declined materially, signaling ongoing financing risk.
Income Statement
22
Negative
Balance Sheet
62
Positive
Cash Flow
28
Negative
BreakdownTTMMar 2026Mar 2025Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue2.94M64.00K26.03M0.000.000.00
Gross Profit2.94M64.00K26.03M0.000.000.00
EBITDA-51.79M-54.58M-14.74M-61.27M-116.74M-201.36M
Net Income-51.79M-55.48M-15.63M-62.11M-118.09M-202.27M
Balance Sheet
Total Assets43.47M56.08M101.28M127.38M174.01M291.05M
Cash, Cash Equivalents and Short-Term Investments31.49M44.34M93.71M118.30M152.42M267.72M
Total Debt596.00K690.00K178.00K465.00K431.00K125.00K
Total Liabilities16.61M14.10M9.12M25.88M16.52M18.80M
Stockholders Equity26.86M41.98M92.17M101.50M157.49M272.26M
Cash Flow
Free Cash Flow-31.93M-51.64M-24.36M-48.22M-103.55M-93.03M
Operating Cash Flow-31.93M-51.21M-23.61M-47.93M-99.27M-85.57M
Investing Cash Flow12.52M9.82M-3.45M75.16M-83.44M-5.34M
Financing Cash Flow19.66M1.09M227.00K-246.00K-91.28K206.66M

Connect Biopharma Holdings Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price2.45
Price Trends
50DMA
2.25
Positive
100DMA
2.36
Negative
200DMA
2.46
Negative
Market Momentum
MACD
0.04
Negative
RSI
51.09
Neutral
STOCH
35.34
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CNTB, the sentiment is Neutral. The current price of 2.45 is above the 20-day moving average (MA) of 2.28, above the 50-day MA of 2.25, and below the 200-day MA of 2.46, indicating a neutral trend. The MACD of 0.04 indicates Negative momentum. The RSI at 51.09 is Neutral, neither overbought nor oversold. The STOCH value of 35.34 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for CNTB.

Connect Biopharma Holdings Risk Analysis

Connect Biopharma Holdings disclosed 111 risk factors in its most recent earnings report. Connect Biopharma Holdings reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Connect Biopharma Holdings Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$6.92M-0.37-127.91%88.77%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$154.29M-2.65-150.47%
45
Neutral
$1.64M-26.63%30.12%-160.47%
42
Neutral
$3.98M-0.14-107.66%95.51%
41
Neutral
$13.52M-0.07-901.32%75.09%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CNTB
Connect Biopharma Holdings
2.33
0.57
32.39%
SCNI
Scinai Immunotherapeutics
2.87
-11.73
-80.34%
GTBP
GT Biopharma
0.29
-0.68
-70.01%
REVB
Revelation Biosciences
0.96
-10.21
-91.44%
DRMA
Dermata Therapeutics
1.61
-3.74
-69.91%
CERO
CERo Therapeutics Holdings
0.01
-7.66
-99.87%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 30, 2026