Stannous Fluoride Dentifrice, Sodium Fluoride Dentifrice, Electric Toothbrush, Cetylpyridinium Chloride (Cpc), Manual Toothbrush
Gingivitis
Phase IV
Completed
A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment Methods
Sep 29, 2025
―
Sodium Monofluorophosphate Dentifrice, Stannous Fluoride Dentifrice, Test Stannous Fluoride Dentifrice
Gingivitis
Phase IV
Active Not Recruiting
Assessing Gingivitis and Plaque From a Marketed Toothpaste
Aug 28, 2025
―
0.76% Sodium Monofluorophosphate Dentifrice, 0.454% Stannous Fluoride Dentifrice
Gingivitis
Phase I
Active Not Recruiting
Evaluating Gingivitis and Systemic Biomarkers
Apr 30, 2025
―
Sodium Monofluorophosphate Dentifrice, Stannous Fluoride Dentifrice, Sodium Fluoride Dentifrice
Gingivitis
Phase II
Completed
Assessing Gingivitis of 3 Different Dentifrices Compared to a Negative Control.
Mar 19, 2025
―
0 Ppm F, 250 Ppm F As Mfp, 1100 Ppm As Mfp, 2800 Ppm F As Mfp
Caries
Phase I
Completed
Salivary Fluoride Clearance
Dec 11, 2024
―
FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Procter & Gamble (PG) have in its pipeline
PG is currently developing the following drugs: Stannous Fluoride Dentifrice, Sodium Fluoride Dentifrice, Electric Toothbrush, Cetylpyridinium Chloride (Cpc), Manual Toothbrush, Sodium Monofluorophosphate Dentifrice, Stannous Fluoride Dentifrice, Test Stannous Fluoride Dentifrice, 0.76% Sodium Monofluorophosphate Dentifrice, 0.454% Stannous Fluoride Dentifrice. These drug candidates are in various stages of clinical development as the company works toward FDA approval.