Pacira Pharmaceuticals (82P) Drug Pipeline
| Drug Name | Condition | Stage | Status | Study Name | Trial Start Date | Article |
|---|---|---|---|---|---|---|
| Zilretta, Triamcinolone Acetonide | Osteoarthritis Of Hip | Phase II | Recruiting | A Study to Evaluate an Intra-Articular Injection of ZILRETTA Versus Triamcinolone Acetonide, Immediate Release in Subjects With Osteoarthritis of the Hip | May 07, 2025 | ― |
| Enekinragene Inzadenovec (Pcrx-201) | Osteoarthritis (Oa) Of The Knee | Phase II | Recruiting | A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee | Mar 13, 2025 | ― |
| Iovera° System, Sham Iovera° System Treatment | Spasticity, Cerebral Or Spinal Condition | Phase III | Recruiting | Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upper Extremity Spasticity | Mar 25, 2024 | ― |
| Zilretta, Tca-Ir | Glenohumeral Osteoarthritis | Phase III | Recruiting | ZILRETTA in Subjects With Shoulder Osteoarthritis | Feb 13, 2024 | ― |
| Bupivacaine, Exparel | Postoperative Pain | Phase I | Recruiting | Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery | Jan 18, 2024 | ― |
| Liposomal Bupivacaine 13.3, Bupivacaine | Healthy | Phase I | Completed | Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupivacaine 13.3 Administered Via a Single Intrathecal Injection to Healthy Volunteers | Jun 22, 2022 | ― |
| Bupivacaine Hcl, Bupivacaine Liposome Injectable Suspension 266 Mg, Bupivacaine Liposome Injectable Suspension 133 Mg | Hallux Valgus, Bunionectomy | Phase III | Completed | Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy | Nov 15, 2021 | ― |
| Fx201 | Osteoarthritis, Knee | Phase I | Active Not Recruiting | Study to Evaluate the Safety and Tolerability of FX201 in Patients with Osteoarthritis of the Knee | Oct 03, 2019 | ― |
| Drug Name | Stage | Condition | Status | Study Name | Trial Start Date | Article |
|---|---|---|---|---|---|---|
| Zilretta, Triamcinolone Acetonide | Phase II | Osteoarthritis Of Hip | Recruiting | A Study to Evaluate an Intra-Articular Injection of ZILRETTA Versus Triamcinolone Acetonide, Immediate Release in Subjects With Osteoarthritis of the Hip | May 07, 2025 | ― |
| Enekinragene Inzadenovec (Pcrx-201) | Phase II | Osteoarthritis (Oa) Of The Knee | Recruiting | A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee | Mar 13, 2025 | ― |
| Iovera° System, Sham Iovera° System Treatment | Phase III | Spasticity, Cerebral Or Spinal Condition | Recruiting | Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upper Extremity Spasticity | Mar 25, 2024 | ― |
| Zilretta, Tca-Ir | Phase III | Glenohumeral Osteoarthritis | Recruiting | ZILRETTA in Subjects With Shoulder Osteoarthritis | Feb 13, 2024 | ― |
| Bupivacaine, Exparel | Phase I | Postoperative Pain | Recruiting | Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery | Jan 18, 2024 | ― |
| Liposomal Bupivacaine 13.3, Bupivacaine | Phase I | Healthy | Completed | Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupivacaine 13.3 Administered Via a Single Intrathecal Injection to Healthy Volunteers | Jun 22, 2022 | ― |
| Bupivacaine Hcl, Bupivacaine Liposome Injectable Suspension 266 Mg, Bupivacaine Liposome Injectable Suspension 133 Mg | Phase III | Hallux Valgus, Bunionectomy | Completed | Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy | Nov 15, 2021 | ― |
| Fx201 | Phase I | Osteoarthritis, Knee | Active Not Recruiting | Study to Evaluate the Safety and Tolerability of FX201 in Patients with Osteoarthritis of the Knee | Oct 03, 2019 | ― |
FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases: a. Preclinical testing b. Phase 1 – Safety and dosage c. Phase 2 – Effectiveness and side effects d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Pacira (CH:82P) have in its pipeline
Pacira Pharmaceuticals CH:82P is currently developing the following drugs: Zilretta, Triamcinolone Acetonide, Enekinragene Inzadenovec (Pcrx-201), Iovera° System, Sham Iovera° System Treatment, Zilretta, Tca-Ir, Bupivacaine, Exparel, Liposomal Bupivacaine 13.3, Bupivacaine, Bupivacaine Hcl, Bupivacaine Liposome Injectable Suspension 266 Mg, Bupivacaine Liposome Injectable Suspension 133 Mg, Fx201. These drug candidates are in various stages of clinical development as the company works toward FDA approval.
