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Bio-Path Holdings (BPTH) AI Stock Analysis

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BPTH

Bio-Path Holdings

(Other OTC:BPTH)

Select Model
Rating:39Underperform
Price Target:$0.02â–²(7900.00% Upside)
Action:reiterated
Date:08/19/26

BPTH scores near the bottom of the range. The dominant factor is a deeply distressed financial profile: no revenue, persistent losses, a shrinking asset base under $700,000, and negative stockholders' equity that raises serious going-concern and insolvency questions. Continued operations depend entirely on external financing that would likely be highly dilutive. Technicals reinforce the negative view, with the stock trading well below all key moving averages and negative MACD momentum; oversold RSI and Stochastic readings suggest only the possibility of short-term bounces, not a trend change. Valuation offers no support given negative earnings, no dividend, and a sub-$0.05 share price. This is an extremely high-risk, speculative situation.

Positive Factors
Low Absolute DebtVery low absolute debt limits immediate interest expense and refinancing demands, giving the company some flexibility while its programs remain in development. This is a relative balance-sheet strength, although it does not eliminate the broader funding challenge created by negative equity and ongoing losses.
Negative Factors
No Commercial RevenueThe absence of revenue means BPTH has not yet demonstrated commercial product demand or an operating model that funds itself. Continued dependence on development progress and eventual approval leaves earnings visibility limited and makes future financial performance highly dependent on pipeline execution.

Bio-Path Holdings (BPTH) vs. SPDR S&P 500 ETF (SPY)

-100%-80%-60%-40%-20%0%20%BPTH-68.75%SPY+14.55%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
$15.09K
Dividend Yield
―
Average Volume (3M)
97.00K
Price to Earnings (P/E)
-0.0
Beta (1Y)
-0.54
Revenue Growth
―
EPS Growth
87.92%
Country
US
Employees
1
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Bio-Path Holdings Business Overview & Revenue Model

Company Description

Bio-Path Holdings, Inc. is a U.S.-based pharmaceutical company focused on developing RNAi nanoparticle drugs for oncology, with programs spanning both clinical and preclinical stages. Its innovative product development is centered around the DNAbiliz...

How the Company Makes Money

As a clinical-stage biotechnology company, BPTH’s ability to generate recurring commercial revenue depends on successful development and eventual regulatory approval of its therapeutic candidates; however, specific, current revenue streams (e.g., pro...

Bio-Path Holdings Earnings Call Summary

Earnings Call Date:Nov 15, 2024(Q3-2024)|% Change Since:-99.97%|Next Earnings Date:May 12, 2023
Earnings Call SentimentPositive

The call highlighted significant advancements in clinical trials and the expansion of the DNAbilize platform into new therapeutic areas, reflecting strong progress in drug development. Despite some financial challenges, such as increased administrative expenses and a decrease in cash position, the overall outlook remains positive due to substantial progress in pipeline advancements and research publications.

Positive Updates

Expansion of DNAbilize Platform
Initiation of clinical development program for BP-1001-A as a treatment for obesity and related metabolic diseases, marking the first non-cancer application of DNAbilize platform.

Negative Updates

Increased General and Administrative Expenses
General and administrative expenses increased to $1.3 million in Q3 2024 from $1.0 million in Q3 2023, primarily due to increased legal fees and salaries.

Company Guidance

In the Bio-Path Holdings Q3 2024 earnings call, the company reported a net loss of $2.1 million, or $0.70 per share, which marks an improvement from the $3.2 million loss, or $6.36 per share, in the same period last year. Research and development expenses decreased to $1.3 million from $2.3 million, attributed to reduced manufacturing costs and clinical trial expenses. General and administrative expenses rose to $1.3 million from $1.0 million, driven by increased legal fees and salaries. The company's cash reserves stood at $0.6 million as of September 30, 2024, down from $1.1 million at the end of 2023, with $7.7 million net cash used in operating activities and $7.2 million generated from financing activities over the first nine months of 2024. Bio-Path is advancing its DNAbilize platform, aiming to expand into obesity and metabolic diseases while progressing clinical trials in oncology.

Bio-Path Holdings Financial Statement Overview

Summary

Financials are severely distressed. Bio-Path has generated zero revenue in every reported period and posted continuous losses, including an $8.7 million net loss in 2025. The balance sheet is the biggest concern: total assets have collapsed from $26.6 million in 2021 to roughly $678,000 in 2025, and stockholders' equity has turned negative at -$8.2 million, signaling book-value insolvency and material going-concern risk. Operating cash flow remains negative, and while the 2025 burn fell to -$1.6 million, this likely reflects a scaling back of clinical activity rather than genuine improvement. The company cannot self-fund and faces imminent, likely highly dilutive, capital-raising needs.

Income Statement

5Very Negative

Balance Sheet

3Very Negative

Cash Flow

8Very Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Mar 2023Dec 2021
Income Statement
Total Revenue000000
Gross Profit-34.00K-96.00K-159.00K-178.00K-178.00K-161.00K
EBITDA-2.09M-8.24M-9.73M-15.66M-13.69M-10.28M
Net Income-4.13M-8.67M-9.89M-16.08M-13.84M-10.44M
Balance Sheet
Total Assets6,000678.00K3.88M3.22M15.97M26.57M
Cash, Cash Equivalents and Short-Term Investments2,00001.17M1.05M10.38M23.77M
Total Debt520.00K463.00K83.00K113.00K221.00K235.00K
Total Liabilities9.69M8.90M3.73M2.78M1.80M1.11M
Stockholders Equity-9.69M-8.22M154.00K441.00K14.17M25.46M
Cash Flow
Free Cash Flow-77.00K-1.60M-10.57M-11.54M-15.12M-9.99M
Operating Cash Flow-77.00K-1.60M-10.57M-11.54M-15.10M-9.92M
Investing Cash Flow0000-21.00K-70.00K
Financing Cash Flow79.00K423.00K10.70M2.20M1.73M20.01M

Bio-Path Holdings Technical Analysis

Technical Analysis SentimentNegative
Last Price0.00

Price Trends

50DMA0.04Negative
100DMA0.04Negative
200DMA0.05Negative

Market Momentum

MACD-0.00Positive
RSI24.47Positive
STOCH48.48Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BPTH, the sentiment is Negative. The current price of 0.00 is below the 20-day moving average (MA) of 0.03, below the 50-day MA of 0.04, and below the 200-day MA of 0.05, indicating a bearish trend. The MACD of -0.00 indicates Positive momentum. The RSI at 24.47 is Positive, neither overbought nor oversold. The STOCH value of 48.48 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BPTH.

Bio-Path Holdings Risk Analysis

Bio-Path Holdings disclosed 47 risk factors in its most recent earnings report. Bio-Path Holdings reported the most risks in the "Finance & Corporate" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy

Latest Risks Added

1 New Risk
1.Unstable market and economic conditions may have serious adverse effects on our ability to raise funds, which may cause delays, restructuring or cessation of our operations.Q4, 2023

Bio-Path Holdings Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

BPTH against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
CLRBCLRB46Neutral$11.65M-0.32-154.53%――66.06%
MBRXMBRX44Neutral$8.46M-0.67-816.56%――85.06%
CLDICLDI41Neutral$2.41M-0.03-372.86%――53.95%
BPTHBPTH39Underperform$15.09K-0.0048.04%――87.92%
MTNBMTNB38Underperform$899.59K-0.05-181.45%――68.91%
NCNANCNA33Underperform$4.01M-0.24-41.95%――99.50%

* Healthcare Sector Average

Performance Comparison

-50%0%BPTHMTNBCLRBMBRXNCNACLDIDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
BPTH and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
BPTHBio-Path Holdings0.03-0.06-70.93%
MTNBMatinas BioPharma Holdings0.90-16.80-94.91%
CLRBCellectar Biosciences Inc1.14-1.78-60.96%
MBRXMoleculin Biotech7.87-204.23-96.29%
NCNANucana Plc0.93-2.27-70.88%
CLDICalidi Biotherapeutics, Inc.0.62-23.38-97.41%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Aug 28, 2026