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BioCryst (BCRX) Stock Price & Analysis
BCRX Stock Chart & Stats
- Day’s Range
- $8.38 - $8.62
- 52-Week Range
- $6.23 - $11.22
- Previous Close
- $8.52
- Volume
- 1.53M
- Average Volume (3M)
- 5.08M
- Market Cap
- $2.16B
- Enterprise Value
- $3.14B
- Total Cash (Recent Filing)
- $352.57M
- Total Debt (Recent Filing)
- $409.86M
- Price to Earnings (P/E)
- ―
- Beta
- 0.60
- Next Earnings
- Nov 04, 2026 (Est.)
- EPS Estimate
- 0.09
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Commercial Revenue Growth
Strong comparable revenue growth and continued ORLADEYO expansion indicate rising commercial adoption of BioCryst’s core therapy. Sustained product demand can support recurring revenue, fund development programs, and reinforce the company’s position in HAE over the next several quarters.
Cash Generation
Recent positive operating and free cash flow provides BioCryst with internally generated funding for commercialization and clinical development. This cash conversion is especially valuable because it can reduce reliance on external financing while supporting operations through upcoming product and trial milestones.
Pediatric Product Expansion
The pediatric pellet launch expands ORLADEYO’s addressable patient population and broadens the product’s utility across age groups. Early prescriptions and approval activity suggest initial commercial traction, creating an additional avenue for durable patient growth beyond the established capsule business.
Bears Say
Strained Balance Sheet
Persistently negative equity and meaningful debt leave BioCryst with limited balance-sheet cushion if operating conditions weaken. The capital structure may constrain financial flexibility, increase sensitivity to execution setbacks, and make it harder to fund future investments without relying on additional financing.
Volatile Profitability
The sharp swing from positive 2025 earnings to a substantial TTM loss shows that reported profitability is not yet consistently durable. Compressed gross margin and negative operating results could limit retained cash generation and reduce the resources available for sustained commercial and R&D investment.
Injectable Competition
Competitive pressure from newer injectable prophylactic treatments could make it harder for ORLADEYO to retain or expand its HAE share, even as the oral product grows. Patient switching may constrain future volume growth and require continued commercial investment to defend the franchise.
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BioCryst Stock Smart Score
Company Description
BioCryst
BioCryst Pharmaceuticals, Inc. is a biotechnology company focused on discovering and developing novel, orally administered, small-molecule therapeutics. The company currently markets two key products: Peramivir injection: An intravenous neuraminidase inhibitor, sold under the brand names RAPIVAB, RAPIACTA, and PERAMIFLU, used for the treatment of acute uncomplicated influenza. ORLADEYO: An oral serine protease inhibitor designed to manage hereditary angioedema. BioCryst's development pipeline includes several promising candidates: BCX9930: An oral factor D inhibitor in Phase II clinical trials for complement-mediated diseases. BCX9250: An oral activin receptor-like kinase-2 inhibitor undergoing Phase I clinical evaluation for fibrodysplasia ossificans progressiva. Galidesivir: An RNA dependent-RNA polymerase inhibitor, also in Phase I, aimed at treating a range of RNA viruses, including Marburg, Yellow Fever, Ebola, and Zika. The company engages in strategic collaborations and in-license agreements with numerous partners. These include pharmaceutical entities like Torii Pharmaceutical Co., Ltd., Seqirus UK Limited, Shionogi & Co., Ltd., Green Cross Corporation, and Mundipharma International Holdings Limited. Their alliances also extend to governmental and academic organizations such as the National Institute of Allergy and Infectious Diseases, the Biomedical Advanced Research and Development Authority, the U.S. Department of Health and Human Services, The University of Alabama at Birmingham, Albert Einstein College of Medicine of Yeshiva University, and Industrial Research, Ltd. Established in 1986, BioCryst Pharmaceuticals, Inc. is headquartered in Durham, North Carolina.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Charles K. Gayer
- Employees
- 435
- Website
- www.biocryst.com
- Address
- 4505 Emperor Boulevard, Durham, NC, 27703, US
BioCryst (BCRX) Earnings & Revenues
BCRX Company Deck
BCRX Earnings Call
Earnings Call SentimentPositive
The call conveyed a predominantly positive operational and financial picture: strong comparable revenue growth (+45% total; ORLADEYO +10% YoY), solid cash balance (~$350M+) and non-GAAP profitability ($113.2M), successful enrollment milestones (navenibart pivotal study completed ahead of schedule), and an initiated pediatric launch with encouraging early demand (47 prescriptions). Management also reinforced financial discipline, tightened operating cost guidance, and secured a €55.7M upfront license payment. Offsetting items include a prior manufacturing delay for pediatric pellets (now shipping), a strategic wind-down of internal discovery and Birmingham facility closure that reduces in-house R&D capacity, continued competition from new injectables, and timing uncertainty for several material clinical data readouts (navenibart top line in Q3 2027; BCX17725 POC by end-2026). On balance, the positive financial and commercial momentum and clear cost discipline outweigh the challenges and transition risks.
View all BCRX earnings summariesBCRX Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 9 | 2 | 11 |
| Technical Analysis | 3 | 2 | 5 |
| Moving Averages | 6 | 0 | 6 |












