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Tryptamine Therapeutics (ENP) AI Stock Analysis

AU:ENP

Tryptamine Therapeutics

(ASX:ENP)

Select Model
Rating:42Neutral
Price Target:AUD 0.03â–¼(-3.23% Downside)
Action:reiterated
Date:10/19/26

The score is driven primarily by very weak financial performance, including zero revenue, persistent losses, and ongoing cash burn. Mixed technical indicators and loss-based valuation provide limited support, resulting in an overall score of 42.

Positive Factors
Debt-free balance sheetA positive equity base with no reported debt reduces refinancing and interest-rate risk while preserving financial flexibility. This gives the company more capacity to direct available resources toward research and development without servicing a current debt burden.
Negative Factors
No recurring revenueThe absence of meaningful recurring revenue confirms that the company has not yet established a commercial revenue engine. Until programs generate product or partnership income, financial progress remains dependent on development milestones and access to external funding.

Tryptamine Therapeutics (ENP) vs. iShares MSCI Australia ETF (EWA)

-40%-30%-20%-10%0%10%20%AU:ENP-22.50%EWA+14.93%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
AUD 47.39M
Dividend Yield
―
Average Volume (3M)
1.57M
Price to Earnings (P/E)
-12.6
Beta (1Y)
0.45
Revenue Growth
―
EPS Growth
29.55%
Country
Australia
Employees
4
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Tryptamine Therapeutics Business Overview & Revenue Model

Company Description

Entropy Neurodynamics Limited operates as a clinical-stage pharmaceutical company, dedicated to pioneering novel formulations for psilocin administration. These formulations are intended for use alongside psychotherapy, aiming to tackle medical condi...

Tryptamine Therapeutics Financial Statement Overview

Summary

Very weak financial performance: revenue was zero, operating and net losses persisted, and operating and free cash flow remained negative. Zero debt and improving equity are positive, but the underlying financial scores produce a result below the permitted range, so the score is set at the minimum of 37.

Income Statement

8Very Negative

Balance Sheet

62Positive

Cash Flow

18Very Negative
Financial statement breakdown
BreakdownTTMJun 2026Aug 2024Jun 2023Jun 2022Jun 2021
Income Statement
Total Revenue0000618.57K99.73K
Gross Profit-27.34K-27.34K-54.34K-6,771618.57K99.73K
EBITDA-6.74M-6.74M-5.27M-6.70M-5.10M-8.27M
Net Income-4.87M-4.87M-5.33M-6.14M-7.13M-10.08M
Balance Sheet
Total Assets8.38M8.38M6.66M7.45M5.88M13.61M
Cash, Cash Equivalents and Short-Term Investments5.58M5.58M3.03M5.37M1.64M4.85M
Total Debt00001.53M3.74M
Total Liabilities1.02M1.02M699.17K1.83M1.75M4.81M
Stockholders Equity7.36M7.36M5.96M5.62M4.13M8.81M
Cash Flow
Free Cash Flow-3.41M-3.41M-7.90M-6.00M-4.03M-9.72M
Operating Cash Flow-3.41M-3.41M-7.77M-6.00M-4.03M-8.59M
Investing Cash Flow-10.41K-10.41K-133.40K1.68M-9,079-1.24M
Financing Cash Flow5.97M5.97M5.60M9.27M2.39M1.95M

Tryptamine Therapeutics Technical Analysis

Technical Analysis SentimentNegative
Last Price0.03

Price Trends

50DMA0.04Negative
100DMA0.04Negative
200DMA0.03Negative

Market Momentum

MACD-0.00Positive
RSI32.71Neutral
STOCH41.07Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:ENP, the sentiment is Negative. The current price of 0.03 is below the 20-day moving average (MA) of 0.03, below the 50-day MA of 0.04, and below the 200-day MA of 0.03, indicating a bearish trend. The MACD of -0.00 indicates Positive momentum. The RSI at 32.71 is Neutral, neither overbought nor oversold. The STOCH value of 41.07 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AU:ENP.

Tryptamine Therapeutics Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

AU:ENP against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
AU:NEUAU:NEU74OutperformAUD 2.58B128.626.03%0.72%-68.00%-86.31%
AU:ZLDAU:ZLD52NeutralAUD 5.95M-1.5680.84%―――
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
AU:ACWAU:ACW44NeutralAUD 162.72M-8.54-103.42%――5.88%
AU:ENPAU:ENP42NeutralAUD 50.66M-12.61-63.60%――29.55%
AU:ATXAU:ATX30UnderperformAUD 43.12M-4.91-18.71%――21.23%

* Healthcare Sector Average

Performance Comparison

0%50%100%AU:ENPAU:ATXAU:ACWAU:NEUAU:ZLDDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
AU:ENP and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
AU:ENPTryptamine Therapeutics Limited0.03-0.01-18.42%
AU:ATXAmplia Therapeutics Ltd.0.08-0.05-37.78%
AU:ACWActinogen Medical Limited0.040.002.50%
AU:NEUNeuren Pharmaceuticals Limited20.750.211.03%
AU:ZLDZelira Therapeutics Ltd.0.500.1335.14%

Tryptamine Therapeutics Corporate Events

Entropy Neurodynamics Boosts Director Equity Through Share-Based Fees

Oct 14, 2026

Entropy Neurodynamics Limited has disclosed a change in director Herwig Janssen’s interests, with the issuance of 623,441 ordinary fully paid shares in lieu of cash fees for services rendered between July and September 2026. This equity-based p...

Entropy Neurodynamics Issues Director Fee Shares, Confirms Regulatory Compliance

Oct 14, 2026

Entropy Neurodynamics Limited has issued 623,441 fully paid ordinary shares to its directors in lieu of cash payment of directors’ fees, as previously approved at its 13 November 2025 Annual General Meeting. The company has lodged the associate...

Entropy Neurodynamics Issues Equity to Directors in Lieu of Cash Fees

Oct 14, 2026

Entropy Neurodynamics Limited, an ASX-listed company in the neurotechnology and neuroscience domain, structures director remuneration so that fees may be paid in shares rather than cash. The use of ordinary fully paid shares for board compensation al...

Entropy Neurodynamics posts 2026 AGM materials and streamlines investor communications

Oct 4, 2026

Entropy Neurodynamics Limited has released key documents for its 2026 Annual General Meeting, including the notice of meeting, a letter of access and proxy form, signalling the next formal step in its governance calendar as a recently listed clinical...

Entropy Neurodynamics Sets Date for 2026 AGM and Director Nomination Deadline

Sep 14, 2026

Entropy Neurodynamics Limited has scheduled its 2026 Annual General Meeting for 12 November 2026 at 4:00pm AEDT in Hawthorn East, Victoria, and has set 24 September 2026 as the closing date for director nominations. The company is also encouraging sh...

Entropy Neurodynamics Reports Durable 12-Week Gains in BED Trial of Psychedelic Therapy TRP-8803

Sep 13, 2026

Entropy Neurodynamics Limited, a clinical-stage biotech in Melbourne, is developing precision-controlled psychedelic therapies, led by its IV-infused psilocin candidate TRP-8803 for treatment-resistant binge eating disorder. The company is building a...

Entropy Neurodynamics to Showcase Psilocin Program in Investor Webinar

Aug 28, 2026

Entropy Neurodynamics Limited, a clinical-stage biotech focused on psilocin-based psychedelic-assisted therapies, is advancing proprietary formulations aimed at treating conditions with unmet medical needs. Its lead candidate, TRP-8803, delivers psil...

Entropy Neurodynamics Files ASX Governance Disclosures for 2026

Aug 28, 2026

Entropy Neurodynamics Limited has lodged its Appendix 4G and corporate governance statement with the ASX for the financial year ended 30 June 2026, confirming board approval and compliance with the exchange’s disclosure framework. The company h...

Entropy Neurodynamics Narrows Annual Loss as Revenue Jumps 30%

Aug 28, 2026

Entropy Neurodynamics Limited operates in the neurodynamics and therapeutics sector, with related entities Tryp Therapeutics Inc in Canada and Tryp Therapeutics (USA) Inc in the U.S. preparing their accounts under IFRS Accounting Standards. The group...

Entropy Neurodynamics Plans U.S. Phase 2 Trial Pitting Psychedelic Therapy Against Lexapro

Aug 26, 2026

Entropy Neurodynamics has signed a pre-Clinical Trial Agreement with the University of California, San Francisco to run a U.S. Phase 2 trial comparing its IV psilocin candidate TRP-8803 against escitalopram in up to 80 young adults with Major Depress...

Entropy Neurodynamics Seeks ASX Quotation for 1 Million New Shares

Aug 24, 2026

Entropy Neurodynamics Limited has lodged a new application with the ASX for the quotation of 1,000,000 ordinary fully paid shares under its existing ENP code, with an issue date of August 21, 2026. The move formalizes the listing of these additional...

Entropy Neurodynamics Seeks Trading Halt Ahead of Key U.S. Phase 2 Trial Update

Aug 24, 2026

Entropy Neurodynamics has requested a trading halt on its ordinary shares from the start of ASX trading on 24 August 2026, with the halt to remain in place until either 26 August 2026 or the release of a pending announcement. The move signals a forth...

Entropy Neurodynamics secures BioCina for global-scale manufacturing of IV psilocin therapy

Aug 18, 2026

Entropy Neurodynamics has signed a Development and Manufacturing Services Agreement with BioCina to produce its proprietary TRP-8803 intravenous psilocin formulation under GMP conditions. The deal secures access to BioCina’s TGA-licensed, FDA-...

Entropy Neurodynamics Boosts Director Equity Through Share-Based Fees

Aug 7, 2026

Entropy Neurodynamics Limited has disclosed a change in director Herwig Janssen’s holdings, reflecting the issuance of additional ordinary fully paid shares. The update was lodged under Australian Securities Exchange requirements, detailing mov...

Entropy Neurodynamics Issues Director Fee Shares, Confirms Regulatory Compliance

Aug 7, 2026

Entropy Neurodynamics has issued 766,871 fully paid ordinary shares to directors in lieu of cash fees, as previously approved at its November 2025 annual general meeting, and has lodged the relevant Appendix 2A with the ASX. The company confirmed it...

Entropy Neurodynamics Issues New Shares in Lieu of Directors’ Fees

Aug 7, 2026

Entropy Neurodynamics Limited has applied to the ASX for quotation of 766,871 ordinary fully paid shares, to be issued on August 7, 2026. These shares are being issued in lieu of cash payment for directors’ fees, following prior approval by sha...

Tryp Therapeutics Showcases World-First Binge Eating Trial in Psychedelic Neuropsychiatry

Aug 6, 2026

Tryp Therapeutics, presented under the Entropy Neurodynamics banner at the Bioshares 2026 Investor Roadshow, is highlighting world-first clinical results in treating resistant binge eating disorder using psychedelic-assisted approaches. The company p...

Entropy Neurodynamics wins approval for multi-indication TRP-8803 basket trial

Aug 3, 2026

Entropy Neurodynamics has secured Human Research Ethics Committee approval and a Clinical Trial Research Agreement with Swinburne University for a Phase 1b/2a basket trial of its IV-infused psilocin therapy TRP-8803 in 72 patients. The world-first st...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Oct 19, 2026