TipRanks
Go Ultimate55% OFF

Collplant Holdings (CLGN) AI Stock Analysis

193 Followers
CLGN

Collplant Holdings

(NASDAQ:CLGN)

Select Model
Rating:44Neutral
Price Target:$4.00â–¼(-2.68% Downside)
Action:reiterated
Date:10/01/26

The score is primarily held down by very weak financial performance (minimal/declining revenue, heavy losses, and sustained cash burn with equity erosion). Technicals are only neutral with the stock still well below its 200-day average, and valuation remains unattractive due to negative earnings and no dividend yield support.

Positive Factors
Proprietary collagen platformCollPlant’s plant-based recombinant human collagen platform supports multiple biomaterial applications, including tissue engineering and 3D bioprinting. This proprietary foundation can support differentiated products and partnerships across regenerative medicine, provided commercialization continues to develop.
Negative Factors
Severe revenue weaknessVery small and declining revenue, combined with deeply negative profitability, indicates that the current business has not yet achieved meaningful commercial scale. Persistent losses reduce earnings visibility and make future performance highly dependent on successful product and technology commercialization.

Collplant Holdings (CLGN) vs. SPDR S&P 500 ETF (SPY)

-100%-80%-60%-40%-20%0%20%CLGN-81.15%SPY+12.53%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
$7.71M
Dividend Yield
―
Average Volume (3M)
367.41K
Price to Earnings (P/E)
-0.4
Beta (1Y)
0.07
Revenue Growth
-86.76%
EPS Growth
16.63%
Country
US
Employees
39
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Collplant Holdings Business Overview & Revenue Model

Company Description

CollPlant Biotechnologies Ltd. is a regenerative and aesthetic medicine enterprise operating across the United States, Canada, and Europe. The company primarily engages in the three-dimensional (3D) bioprinting of tissues and organs, alongside develo...

Collplant Holdings Earnings Call Summary

Earnings Call Date:Mar 25, 2025(Q4-2024)|% Change Since:-85.32%|Next Earnings Date:May 29, 2019
Earnings Call SentimentNeutral

Despite significant advancements in preclinical programs and continued collaboration with AbbVie, the company experienced a sharp decline in annual revenue and increased net losses, presenting a mixed financial outlook.

Positive Updates

Photocurable Dermal Filler Preclinical Success
The photocurable dermal filler candidate is in the preclinical phase, targeting a market valued at approximately $6.3 billion with a compound annual growth rate of 10%. Positive feedback from leaders in aesthetic medicine suggests it could be a game-changer for facial plastic surgery.

Negative Updates

Significant Revenue Decline
Revenue for the year ended December 31, 2024, was $515,000, a sharp decrease from $11 million in 2023, mainly due to a $10 million milestone payment in 2023 not repeated in 2024.

Company Guidance

During the CollPlant Biotechnologies Ltd. investor call, CEO Yehiel Tal and Deputy CEO Eran Rotem provided guidance centered on their regenerative medicine advancements, notably highlighting their proprietary photocurable dermal filler and regenerative breast implant programs. The dermal filler, aimed at a market valued at approximately $6.3 billion with a 10% CAGR, is currently in the preclinical phase, with plans to launch a clinical trial within two years. The regenerative breast implant program is progressing with preclinical testing of 250cc commercial-sized prototypes, showing promising results in tissue integration without complications. Financially, CollPlant reported a decrease in revenue from $11 million in 2023 to $515,000 in 2024, primarily due to a $10 million milestone payment from AbbVie in 2023. Despite a GAAP net loss of $16.6 million in 2024 compared to $7 million in 2023, the company maintains a stable cash position of $11.9 million as of December 31, 2024, not accounting for an additional $2 million payment from AbbVie, ensuring operational capability into the second quarter of 2026.

Collplant Holdings Financial Statement Overview

Summary

Overall fundamentals are very weak: revenue is very small and declining, profitability is deeply negative, and losses remain substantial. Cash flow is consistently negative with ongoing cash burn, while the balance sheet shows only moderate leverage but a sharply shrinking equity base that raises financing risk.

Income Statement

12Very Negative

Balance Sheet

38Negative

Cash Flow

14Very Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Mar 2024Dec 2022Dec 2021
Income Statement
Total Revenue318.00K2.37M515.00K10.96M299.00K15.64M
Gross Profit-1.66M624.00K-2.15M7.87M-1.18M13.64M
EBITDA-11.52M-10.56M-15.55M-5.91M-15.81M1.05M
Net Income-12.51M-11.49M-16.61M-7.02M-16.93M237.00K
Balance Sheet
Total Assets7.20M10.79M18.71M34.13M37.77M51.22M
Cash, Cash Equivalents and Short-Term Investments2.95M5.95M11.91M26.67M29.65M43.30M
Total Debt2.66M2.85M3.08M3.16M2.91M3.61M
Total Liabilities4.25M4.70M5.25M5.79M5.49M6.10M
Stockholders Equity2.94M6.08M13.46M28.34M32.28M45.12M
Cash Flow
Free Cash Flow-11.70M-9.45M-14.58M-3.72M-14.97M1.07M
Operating Cash Flow-11.61M-9.42M-14.09M-2.76M-13.70M2.50M
Investing Cash Flow-8,883-27.00K-539.00K-1.16M28.92M-31.56M
Financing Cash Flow2.45M3.10M9,0001.11M1.87M38.76M

Collplant Holdings Technical Analysis

Technical Analysis SentimentPositive
Last Price4.11

Price Trends

50DMA3.71Positive
100DMA3.51Positive
200DMA5.05Negative

Market Momentum

MACD0.11Negative
RSI55.04Neutral
STOCH61.76Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CLGN, the sentiment is Positive. The current price of 4.11 is above the 20-day moving average (MA) of 3.82, above the 50-day MA of 3.71, and below the 200-day MA of 5.05, indicating a neutral trend. The MACD of 0.11 indicates Negative momentum. The RSI at 55.04 is Neutral, neither overbought nor oversold. The STOCH value of 61.76 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CLGN.

Collplant Holdings Risk Analysis

Collplant Holdings disclosed 81 risk factors in its most recent earnings report. Collplant Holdings reported the most risks in the "Finance & Corporate" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy

Latest Risks Added

0 New Risks

Collplant Holdings Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

CLGN against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
PYPDPYPD56Neutral$110.09M-3.69-311.07%――61.30%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
DAREDARE45Neutral$12.88M-0.82-748.08%―――
CLGNCLGN44Neutral$7.71M-0.44-215.58%―-86.76%16.63%
NRSNNRSN41Neutral$2.71M-0.18610.97%―――
PASGPASG41Neutral$10.68M-0.30-218.59%――38.14%
SABSSABS39Underperform$300.26M0.87-6.74%―-100.00%95.16%

* Healthcare Sector Average

Performance Comparison

0%100%CLGNDAREPASGPYPDSABSNRSNDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
CLGN and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
CLGNCollPlant Biotechnologies Ltd.4.11-17.79-81.23%
DAREDaré Bioscience0.65-1.19-64.67%
PASGPassage Bio, Inc.3.40-3.30-49.25%
PYPDPolyPid Ltd.5.461.6744.06%
SABSSab Biotherapeutics, Inc.3.12-0.06-1.89%
NRSNNeurosense Therapeutics Ltd.1.28-19.69-93.90%

Collplant Holdings Corporate Events

CollPlant Names Eran Rotem CEO as Cost-Cutting Plan Ends Regenerative Medicine R&D

Nov 2, 2026

CollPlant Biotechnologies, an Israel-based biotechnology company focused on biofabrication materials, produces recombinant human collagen (rhCollagen) and rhCollagen-based bioinks for regenerative medicine and three-dimensional bioprinting applicatio...

CollPlant Subsidiary LightSolver Wins Israel Defense Ministry Deal for Photonic Computing

Oct 29, 2026

On October 29, 2026, CollPlant’s subsidiary LightSolver signed a paid multi-year framework agreement with the Israel Ministry of Defense’s Directorate of Defense Research & Development to develop and deliver its Laser Processing Unit...

CollPlant Biotechnologies Raises $3.7 Million in October Private Placement

Oct 15, 2026

On October 9, 2026, CollPlant Biotechnologies Ltd. entered into a securities purchase agreement with institutional investors for a private placement of ordinary shares, pre-funded warrants and ordinary warrants, with the offering closing on October 1...

CollPlant Raises $3.7 Million to Accelerate LightSolver Laser Supercomputing

Oct 9, 2026

On October 9, 2026, CollPlant Biotechnologies announced it had entered into definitive agreements for a $3.7 million private placement of ordinary shares and accompanying warrants, led primarily by existing investors. The deal, priced at about $3.74...

CollPlant’s LightSolver Files U.S. Patent to Expand Photonic Computing for Advanced Simulations

Oct 6, 2026

On October 6, 2026, CollPlant Biotechnologies announced that its subsidiary LightSolver filed a U.S. provisional patent application covering a new method to configure its programmable analog, all-optical laser processor for solving inhomogeneous boun...

CollPlant Deepens Photonic Computing Push with LightSolver Deal as Q2 Loss Narrows

Sep 30, 2026

On September 30, 2026, CollPlant reported second-quarter 2026 results showing GAAP revenues of $108,000, down from $179,000 a year earlier, and a GAAP net loss of $2.7 million, reflecting lower rhCollagen product sales and the absence of a prior-year...

CollPlant’s LightSolver Reports Major Photonic Computing Breakthrough in HPC Study

Sep 24, 2026

On September 24, 2026, CollPlant subsidiary LightSolver and Germany’s High-Performance Computing Center Stuttgart published joint research showing that LightSolver’s pure photonic Laser Processing Unit architecture can dramatically speed...

CollPlant Regains Nasdaq Bid Price Compliance, Shoring Up Dual Tech Strategy

Sep 22, 2026

On September 22, 2026, CollPlant Biotechnologies Ltd., a deep-tech and biotech firm, disclosed that it had regained compliance with Nasdaq’s minimum bid price rule after shares closed at or above $1.00 for ten consecutive sessions earlier in th...

CollPlant Highlights LightSolver Optical Computing Strategy in Updated September 2026 Presentation

Sep 18, 2026

On September 17, 2026, CollPlant Biotechnologies posted an updated corporate presentation highlighting its planned acquisition and commercialization of LightSolver, a developer of optical high-performance computing systems that use interacting lasers...

CollPlant Adds LightSolver Founder to Board After Closing Photonic Computing Acquisition

Sep 4, 2026

CollPlant Biotechnologies announced on September 4, 2026 that it has appointed Dr. Ruti Ben Shlomi, CEO and co-founder of LightSolver Ltd., to its Board of Directors following the closing of CollPlant’s acquisition of LightSolver. Her appointme...

CollPlant Closes LightSolver Acquisition, Expands Into Photonic Computing

Sep 3, 2026

On September 3, 2026, CollPlant Biotechnologies closed its acquisition of Israeli deep-tech firm LightSolver, marking its formal entry into the high-performance computing and photonics sectors. The deal, structured primarily in equity with an additio...

CollPlant Biotechnologies Implements 1-for-10 Reverse Share Split to Maintain Nasdaq Listing

Sep 1, 2026

CollPlant Biotechnologies announced that its board approved a one-for-ten reverse share split of its ordinary shares, following shareholder approval at an extraordinary general meeting on August 18, 2026. The reverse split will take effect when tradi...

CollPlant to Acquire LightSolver, Pivoting Into Photonic Supercomputing

Aug 31, 2026

CollPlant Biotechnologies Ltd., based in Rehovot, Israel, operates at the intersection of regenerative medicine and advanced high‑performance computing. In healthcare, it develops recombinant human collagen-based products for 3D bioprinting of...

CollPlant Shareholders Approve All Proposals at August 18 Extraordinary Meeting

Aug 18, 2026

On August 18, 2026, CollPlant Biotechnologies Ltd. held an Extraordinary General Meeting of Shareholders in Israel as part of its ongoing corporate governance processes. The meeting followed a formal notice issued on July 28, 2026 to investors pursua...

CollPlant Biotechnologies Bolsters Authorized Share Capital and Validates Resale Shares After July Private Placement

Aug 6, 2026

On August 6, 2026, CollPlant Biotechnologies filed a Form 6-K in the U.S. to report that its shareholders had previously approved, on July 29, 2026, a substantial increase in authorized share capital from 30 million to 500 million ordinary shares. Th...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Oct 01, 2026