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Zentalis price target lowered to $12 from $45 at Guggenheim

Guggenheim lowered the firm’s price target on Zentalis to $12 from $45 and keeps a Buy rating on the shares after the FDA placed a partial clinical hold on 3 ongoing clinical studies of azenosertib following two recent deaths in the DENALI ovarian cancer Phase I/II study. Guggenheim says this is a major setback for Zentalis and expects the stock to remain under pressure until more clarity is provided, the analyst tells investors in a research note. The firm believes clinical holds similar to this generally tend to be lifted after implementation of additional safety measures and protocol adjustments, which could offer a path to potential resolution.

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