Voyager announces first participants dosed in Phase 1 SAD trial of VY-TAU01

Voyager Therapeutics announced that the first participants were dosed in a Phase 1a single ascending dose, SAD, trial of VY-TAU01, an investigational anti-tau antibody developed to inhibit the spread of pathological tau in Alzheimer’s disease. The objective of the randomized, double-blind, placebo-controlled, SAD trial is to evaluate the safety and pharmacokinetics of VY-TAU01 in healthy adult volunteers. “The initiation of clinical development of VY-TAU01 for the treatment of Alzheimer’s disease is an important milestone for Voyager; it demonstrates the executional abilities of our neurology drug development team, which will be central to our advancement of three wholly-owned and partnered neurology gene therapies towards IND filings next year,” said Toby Ferguson, M.D., Ph.D., Chief Medical Officer of Voyager Therapeutics.