Oppenheimer lowered the firm’s price target on Viridian Therapeutics to $28 from $31 and keeps an Outperform rating on the shares. Top line data from VRDN-001’s pivotal THRIVE trial in active thyroid eye disease remain on track for September, and the firm’s recent scenario analysis supports favorable risk-reward. Although efficacy and safety demonstrated therein as well as in the THRIVE-2 trial in chronic TED will be closely scrutinized relative to Tepezza, Oppenheimer expects -001’s lower administration burden to serve as a competitive commercial advantage should clinical profiles lack differentiation.
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