Verrica announces dosing of first patient in Part 2 Phase 2 study of VP-315

Verrica Pharmaceutical announced that the first patient has been dosed in Part 2 of a Phase 2 study evaluating the Company’s potentially first-in-class oncolytic peptide, VP-315, for the treatment of basal cell carcinoma. Part 2 of the Phase 2 trial is designed to further explore dosing regimens to identify the recommended dose for Part 3 of the study, which is expected to start in the first half of 2024. "Our advancement into Part 2 of our ongoing Phase 2 study in basal cell carcinoma is based on the positive results from Part 1 of the study, where VP-315 demonstrated a favorable safety and tolerability profile, and showed clinical evidence of activity in patients who received a higher dose range," said Ted White, Verrica’s President and Chief Executive Officer. "As a novel oncolytic peptide administered directly at the tumor site, VP-315 has the potential to offer a non-surgical alternative for the approximately three to four million cases of basal cell carcinoma diagnosed in the U.S. each year."