Theratechnologies doses first patient in trial of sudocetaxel zendusortide

Theratechnologies announced dosing of the first participant in Part 3 of its Phase 1 clinical trial of sudocetaxel zendusortide in patients with advanced ovarian cancer. Sudocetaxel zendusortide is an investigational, first-in-class peptide-drug conjugate that targets the sortilin receptor and expedites the internalization and delivery of a cytotoxic payload directly into cancer cells. “We are excited to dose the first of six patients in Part 3 of the Phase 1 trial of sudocetaxel zendusortide with its modified design and dosing regimen,” said Christian Marsolais, Ph.D., Senior Vice President and Chief Medical Officer at Theratechnologies. “We look forward to building on the efficacy we’ve observed so far, which is mainly long-term disease stabilization in a number of advanced patients. This first-patient-dosed milestone, thus extends the momentum of our oncology clinical development program.”