Tevogen R&D leadership discusses promise of T Cell therapy

Dr. Neal Flomenberg and Dr. Lori Grosso of Tevogen Bio Holding discussed the promise of T cell therapy and Tevogen’s mission to make it mainstream on Nasdaq’s broadcast, Live From MarketSite with Kristina Ayanian. Dr. Lori Grosso, Clinical Development Lead, spoke to advances made with genetically modified T cell therapies but noted that patient affordability, tolerability, and accessibility barriers have prevented broader adoption. She noted that unlike genetically modified autologous T cells which produce one treatment dose per patient, Tevogen’s ExacTcell platform produced hundreds of doses from a single donor for its successful phase I clinical trial. In terms of safety, this trial, the results of which were recently published in the journal Blood Advances, showed no dose-limiting toxicities or significant adverse events related to Tevogen’s investigational therapy. Dr. Neal Flomenberg, Chief Scientific Officer, discussed the company’s goal of making cytotoxic T cell immunotherapy a routine, outpatient treatment, which he felt was achievable if the therapy was safe, affordable, readily and rapidly accessible, and comfortable for patients. He noted that cytotoxic T cell therapy harnessed one of nature’s most powerful tools to treat disease and that continued development of this type of therapy, as well as efforts to make it highly accessible to all patients, would be beneficial to large portions of the population.