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Sarepta downgraded to Neutral from Overweight at Piper Sandler

Piper Sandler downgraded Sarepta (SRPT) to Neutral from Overweight with a price target of $36, down from $70. The company announced that a second non-ambulatory patient has died due to acute liver failure due to Elevidys, prompting a decision to suspend commercial shipments of Elevidys in the non-ambulatory setting and pause dosing in ENVISION until an enhanced immunosuppression regimen is approved, the analyst tells investors in a research note. Piper expects sales in ambulatory setting to also be negatively impacted and cut its Elevidys peak sales estimate to $1.7B from $2.4B.

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