Regulus Therapeutics initiated screening in the of the fourth cohort of patients in the Phase 1b MAD study of RGSL8429 for the treatment of ADPKD. Patients in the fourth cohort will receive an open label fixed dose of 300 mg of RGLS8429 every other week for three months. Regulus’ team expects to share further updates as they become available, including topline data from the third cohort in the middle of this year.
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