Provectus announces publication of preclinical research on PV-10

Provectus (PVCT) Biopharmaceuticals announced the publication of independent preclinical research by Aru Narendran, MD, PhD and colleagues at the University of Calgary’s Cumming School of Medicine in Human Vaccines & Immunotherapeutics. Their paper demonstrates that PV-10, a formulation of the Company’s proprietary, pharmaceutical-grade active pharmaceutical ingredient rose bengal sodium, activates the body’s natural STING immune pathway, leading to stronger antigen presentation and more robust T-cell responses. This novel STING-pathway mechanism suggests that PV-10 could potentially represent a safer, more efficacious, and differentiated alternative to widely used vaccine adjuvants such as aluminum salts, emulsions, saponins, and nucleic acid-based fragments, many of which face questions around safety, reactogenicity, and long-term impact.