JPMorgan downgraded Prime Medicine (PRME) to Neutral from Overweight without a price target The company announced that it is deprioritizing its chronic granulomatous disease program, turning over leadership and reducing headcount, the analyst tells investors in a research note. The firm says that while the strategic prioritization looks “prudent,” Prime’s resulting clinical catalyst outlook gets pushed back beyond its current first half of 2026 cash runway. With net cash $1 per share, the stock will like be range bound pending better visibility on development timelines and reach within key pipeline programs, contends JPMorgan.
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