PainReform announces study observations on delivery method for PRF-110

PainReform announced the successful determination of the optimal delivery method for PRF-110 in bunionectomy procedures. This achievement marks a significant milestone aimed at advancing PRF-110 as a leading post-surgical pain management solution. Key Findings from the Phase III Study: PRF-110 was observed to provide thorough coverage of both nerve endings and surrounding tissue surfaces. This is crucial for maximizing pain relief, as full coverage ensures that the product remains in place throughout wound closure and delivers the intended dose directly to the target area. PRF-110 demonstrated superior adhesion and location adherence over the wound bed. Additionally, PRF-110 resolved another competitor’s product issue, being too viscous and becoming increasingly difficult to manage when interacting with physiological fluids. PRF-110 exhibited optimal viscosity and uniformity, maintaining its effectiveness even in the presence of physiological fluids. To ensure comprehensive coverage within the wound geometry, PRF-110 was administered using a cannula connected to the syringe’s Luer lock. This method enabled precise delivery to all parts of the wound, further enhancing the product’s therapeutic impact.