Ocuphire Pharma presents APX3330 ZETA-1 data at CTS 2023

Ocuphire Pharma announced that a presentation titled, Safety and Efficacy of an Oral Therapeutic APX3330 from ZETA-1 Phase 2 Trial in Patients with Diabetic Retinopathy, was delivered by David Lally, M.D. F.A.S.R.S. at the Clinical Trials at the Summit 2023 meeting in Park City, Utah on Saturday, June 10. Dr. Lally is a member of Ocuphire’s Medical Advisory Board. APX3330 was evaluated in patients with mild to moderate non-proliferative diabetic retinopathy and mild proliferative diabetic retinopathy. “We were pleased to have had another opportunity to share the data from our ZETA-1 trial with the retina community at this year’s CTS,” said Rick Rodgers, Interim Chief Executive Officer. “The ZETA-1 trial achieved statistical significance for APX3330 preventing clinically meaningful progression of diabetic retinopathy, as measured by the percentage of subjects with binocular improvement/worsening in DRSS. This is a potential registration endpoint. We are now preparing for an End-of-Phase 2 meeting with the FDA to confirm Phase 3 registration endpoints and study parameters.”