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Merck initiates three Phase 2b trials evaluating tulisokibart

Merck (MRK) announced it has initiated three Phase 2b trials evaluating the safety and efficacy of tulisokibart, an investigational humanized monoclonal antibody targeting tumor necrosis factor-like cytokine 1A, in patients with three immune-mediated inflammatory diseases: MK-7240-12 (NCT06956235) studying patients with moderate to severe hidradenitis suppurativa; MK-7240-013 (NCT07133633) studying patients with radiographic axial spondyloarthritis (r-axSpA; also known as ankylosing spondylitis); MK-7240-014 (NCT07176390) studying patients with rheumatoid arthritis. Global recruitment of these trials has begun, targeting enrollment of more than 640 patients across the three studies.

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