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MediciNova’s MN-166 does not show efficacy in alcoholism trial

MediciNova presented the results of the Phase 2b trial of MN-166 – ibudilast – in alcohol use disorder at the 46th Annual Research Society on Alcoholism Scientific Meeting held June 24 – 28 in Bellevue. The clinical trial was funded by the National Institute on Alcohol Abuse and Alcoholism, a component of the National Institutes of Health. The primary objective of the trial was to evaluate the effects of MN-166 vs. placebo on percent heavy drinking days over the course of a 12-week treatment period. MN-166 treatment was not superior to placebo for reducing percent heavy drinking days. Also, MN-166 treatment was not superior to placebo for the secondary endpoints.

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