Lexaria Bioscience starts study evaluating DehydraTECH-CBD on diabetes

Lexaria Bioscience announces that study program DIAB-A22-1 is expected to begin on schedule today. This is Lexaria’s first-ever study to investigate whether its patented DehydraTECH-processed cannabidiol may potentially have therapeutic utility against diabetes. Lexaria has previously evidenced the safety and efficacy of DehydraTECH-CBD in human hypertension studies. There are strong connections between heart disease, hypertension, and diabetes: hypertension is twice as frequent in diabetics and hypertensive patients are at greater risk of developing diabetes. Diabetes prevents the body from making enough insulin, resulting in abnormal blood sugar levels. It is the 7th largest cause of death in the US and there is currently no cure. Investigation of CBD related to diabetes is in early stages, though there are some areas of ongoing investigation. CBD has shown some ability to reduce the incidence of diabetes in mice. Study DIAB-A22-1 is a dose-ranging, 56-day program in a total of 32 male Zucker rats, 24 obese and 8 lean, that will compare weight gain, blood glucose, cholesterol and trigyceride levels in animals that receive DehydraTECH-CBD to those that do not. The first 28 days of the study is a baseline validation and monitoring phase and the second 28 days of the study will include the daily DehydraTECH-CBD dosing and treatment phase. Blood will be drawn for analysis on days 0, 13, and 27 during the validation phase, and on days 7, 14 and 28 during the treatment phase. Study DIAB-A22-1 will be undertaken by a leading, third-party testing laboratory located in Canada. The laboratory work is expected to complete in early January 2023 with data and reporting to follow thereafter. Lexaria will provide further updates and any relevant material findings in due course from this study as they become available.