Lantern Pharma announced that it has formed a wholly-owned subsidiary, Starlight Therapeutics to develop drug candidate LP-184’s central nervous system, CNS, and brain cancer indications, including glioblastoma, GBM,, brain metastases and several rare pediatric CNS cancers. Starlight will refer to the molecule LP-184, as it is developed in CNS indications, as "STAR-001". Combined, STAR-001’s targeted treatment indications are estimated to represent an annual global market potential of approximately $6B and over 500,000 global cases. Starlight plans on establishing a leading CNS oncology franchise to develop the unique drug candidate STAR-001 for some of the most malignant and unaddressed primary and secondary CNS cancers. The programs being developed by Starlight were born from the analysis of billions of oncology-focused data points and by using Lantern’s AI platform, RADR. STAR-001’s powerful anti-tumor mechanism of action, synthetic lethality, and collaborations with internationally recognized institutions, including the Kennedy Krieger Institute at Johns Hopkins and the Greehey Children’s Cancer Research Institute at UT Health – San Antonio, make it well positioned to advance in targeted and efficient clinical development programs. Starlight intends to pursue human clinical trials for multiple CNS indications starting in late 2023, building on prior IND-enabling studies and the Phase 1 clinical testing that will be conducted by Lantern. "The formation of Starlight allows Lantern to put extreme focus on advancing STAR-001 through targeted clinical trials and dedicate increased time, resources, and personnel to progress one of the most promising drug candidates for CNS cancer patients in decades," stated Panna Sharma, Lantern’s CEO and President. "Additionally, establishing Starlight as a wholly-owned subsidiary will increase the potential to partner with other biopharma companies who are looking to develop a franchise in CNS cancers and to further accelerate the progression of STAR-001 towards changing patient outcomes in this devastating set of diseases," continued Sharma.
Published first on TheFly
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