Jaguar Health’s Napo completes last patient visit for Phase 3 OnTarget trial

Napo Pharmaceuticals announced that the last patient has completed their final visit for the stage 1 primary endpoint treatment period of Napo’s pivotal Phase 3 OnTarget trial of crofelemer for preventive treatment of diarrhea in adult cancer patients with solid tumors receiving targeted therapy with or without standard chemotherapy. This trial is studying an indication Napo also refers to as preventive treatment of chemotherapy-induced overactive bowel – which includes symptoms such as chronic debilitating diarrhea (loose and/or watery stools), urgency, and bowel incontinence. Top-line results for the primary endpoint in this trial are expected the last week of October 2023.