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Intensity Therapeutics downgraded to Hold from Buy at Brookline

Brookline downgraded Intensity Therapeutics (INTS) to Hold from Buy and suspended the firm’s price target pending visibility into additional funding. A global Phase 3 open label, randomized, superiority trial is ongoing in metastatic sarcoma, evaluating INT230-6 monotherapy as an intratrumoral treatment compared to the standard of care in second and third line treatment in soft tissue sarcoma subtypes, notes the analyst, who points out that enrollment completion is expected in the first half of 2026, with data readouts expected based on the number of deaths in the trial.

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