Inozyme Pharma announced that it will share topline pharmacokinetic, pharmacodynamic and safety data from the ongoing Phase 1/2 clinical trials of INZ-701 in ENPP1 Deficiency and ABCC6 Deficiency at a virtual Investor and Analyst Event on Thursday, Feb. 16, 2023. "In 2022 we generated the first evidence that INZ-701 can drive a pharmacodynamic effect on PPi, a key regulator of mineralization, which is integral to the biology of our lead indications. In our ENPP1 Deficiency trial, we observed a rapid, significant, and sustained elevation of PPi at the lowest dose cohort. We also saw promising PPi elevation in our ABCC6 Deficiency trial, with a rapid initial increase at the lowest dose of INZ-701. We look forward to sharing data from all dose cohorts in these ongoing Phase 1/2 trials at our virtual Investor and Analyst event in February," said Axel Bolte, MSc, MBA, Inozyme’s co-founder, president, and chief executive officer.
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