GRI Bio announces article on iNKT cell review in Frontiers in Immunology

GRI Bio announced the publication of an article that reviews data in both experimental models and in humans that suggest a key role of type 1 invariant NKT, iNKT, cell activation in the progression of inflammatory cascades leading to recruitment of neutrophils and activation of the inflammasome, macrophages, fibroblasts, and, ultimately, fibrosis. The manuscript titled, “Type 1 invariant natural killer T cells in chronic inflammation and tissue fibrosis,” has been published in Frontiers in Immunology. “We continue to establish a growing body of data highlighting the positive effect of targeting the immune response earlier in the inflammatory cascade to interrupt disease progression. Our belief in the potential of our NKT platform technology continues to build and we remain focused on leveraging its potential to develop novel biomarkers and therapeutic targets that differentiate stages of fibrosis progression,” commented Marc Hertz, PhD, Chief Executive Officer of GRI Bio. “Supported by this compelling emerging data in experimental models of fibrosis, our team continues to make solid progress in the advancement of our lead programs, GRI-0621 and GRI-0803. We believe GRI is poised to interrupt disease progression and importantly, provide benefit to patients.”