Enveric Biosciences announces presentation of two posters at conference

Enveric Biosciences announced the presentation of two posters at the Canadian Chemical Engineering Conference which was held October 29th to November 1, 2023. The first poster entitled, “Biocatalytic production of MDMA and other phenylpropylamine derivatives,” presented an alternative process for MDMA production integrating yeast-based bioconversion and biocatalytic steps. First, the Enveric research team achieved the production of milligram quantities of pure compounds in small-scale batch fermentations. The second step of MDMA bioproduction involved transamination and was achieved using a biocatalytic approach, which proved to be more efficient compared with yeast-based conversion. The purified transamination products were converted to methamphetamine derivatives, including MDMA, by chemical reduction and N-methylation. The second poster entitled, “A synthetic biology platform for the production of novel indolethylamine derivatives as drug candidates to treat anxiety and depression,” presented bioproduction platforms, which offer an emerging alternative to traditional chemical synthesis of psychedelic-inspired molecules with a reduced hallucinogenic potential and sustained therapeutic benefits. The presentation described a collection of biosynthetic tools, including known and previously unidentified biocatalysts, enabling the production of greater than350 indolethylamine derivatives from simple indolic precursors.