Enveric announces new patent related to EB-373 psilocin prodrug for anxiety

Enveric Biosciences announced that the United States Patent and Trademark Office, USPTO, has issued U.S. Patent No. 11,746,087, titled “C-4 Carboxylic Acid Substituted Tryptamine Derivatives and Methods of Using,” pertaining to the Company’s EVM201 Series and lead candidate EB-373, a psilocin prodrug being developed for the treatment of anxiety disorder. Issued September 5 the new patent provides Enveric with intellectual property rights for compositions and methods for tryptamine-derived prodrugs utilizing C4 carboxylic acid substituted tryptamine derivatives. This patent complements the recently issued U.S. patent titled “C4-Carbonothioate-substituted Tryptamine Derivatives and Methods of Using,” providing Enveric with a robust intellectual property portfolio governing psilocin prodrugs designed to potentially elicit a more rapid onset of action, more controlled therapeutic effect, and reduced gastrointestinal side-effects compared to conventional psilocin prodrugs, such as psilocybin. EB-373 was developed from Enveric’s EVM201 Series of molecules, which are rationally designed to achieve altered metabolic and pharmacokinetic properties. “Today’s patent issuance from the USPTO adds another important pillar to Enveric’s intellectual property portfolio as we continue to distinguish our tryptamine-based prodrugs from similar compounds being developed for the treatment of mental health disorders,” said Joseph Tucker, Ph.D., Director and CEO of Enveric. “Both our EVM201 Series, led by EB-373, and our EVM301 Series are designed to capitalize on the potential of neuroplastogens that can enhance neuroplasticity while minimizing unwanted side effects, including prolonged and unpredictable hallucinatory experiences. We expect continued positive IP-related developments in the coming months that, we believe, will serve to further highlight the differentiation and value of EB-373 and our EVM201 and EVM301 Series of compounds.”