electroCore announces publication of manuscript on VNS

electroCore announced the publication of a peer reviewed manuscript, Effect of Transcutaneous Cervical Vagus Nerve Stimulation, VNS, on Declarative and Working Memory in Patients with Posttraumatic Stress Disorder: A Pilot Study, in the Journal of Affective Disorders. The study was conducted with the support of Emory University, The Georgia Institute of Technology and the Atlanta Veteran’s Affairs Medical Center and was sponsored by a Department of Defense Small Business Technology Transfer grant. Vagus Nerve Stimulation has been shown in preliminary studies to enhance function when paired with cognitive and motor tasks. The randomized double-blinded study enrolled fifteen patients, was conducted over the course of three months of twice daily home-based nVNS self-administered treatments and assessed the effectiveness of nVNS on declarative and working memory in patients with PTSD. The study concluded the active group developed better attention and recall of paragraphs encoded with stimulation as well as for working memory tasks as compared to sham. The improvement in working memory for patients with PTSD who used nVNS compared to sham was statistically significant at 4 weeks and continued to improve through 8 weeks.