Dyadic International announces achievement of milestone payments

Dyadic International (DYAI) announced the achievement of additional milestone payments in its collaborations with Proliant Health & Biologicals in life sciences and Inzymes in food and nutrition, along with updates on its business transformation and commercial progress. Recombinant Human Albumin: In Q3 2025, Dyadic reached a milestone in productivity, achieving a $500,000 milestone, with payment anticipated in Q4 2025. Additional revenue growth is expected as commercialization advances. Proliant has started sampling the product, with the commercial launch targeted for late 2025 and early 2026. Recombinant Transferrin: Sampling efforts are expanding in research, diagnostic and cultured meat markets. Initial production of lab-grade non-animal transferrin products is underway to meet current OEM and supply opportunities. Validation is ongoing with research and diagnostic customers. Recombinant DNase I: Dyadic’s DNase I has successfully met required performance benchmarks for activity and purity, validating its utility in molecular biology, diagnostics, and biopharma applications. Dyadic is currently producing its DNase I at research grade to support direct sales and OEM supply opportunities. Recombinant Alpha-Lactalbumin: A term sheet has been signed for the development of non-animal human alpha-lactalbumin for use in the infant nutrition market. Initial sampling of non-animal bovine alpha-lactalbumin for food and nutrition markets is in progress, and licensing discussions are underway with potential partners. Non-Animal Dairy Enzymes: Dyadic received a $250,000 milestone payment following the achievement of productivity improvements in Q3 2025. The first enzyme’s scale-up is on track for a late 2025 launch, with additional enzyme candidates advancing as part of this partnership.